2cxj

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{{Seed}}
 
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[[Image:2cxj.png|left|200px]]
 
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<!--
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==3D Solution Structure of S100A13==
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The line below this paragraph, containing "STRUCTURE_2cxj", creates the "Structure Box" on the page.
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<StructureSection load='2cxj' size='340' side='right'caption='[[2cxj]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2cxj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CXJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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-->
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cxj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxj OCA], [https://pdbe.org/2cxj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cxj RCSB], [https://www.ebi.ac.uk/pdbsum/2cxj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cxj ProSAT]</span></td></tr>
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{{STRUCTURE_2cxj| PDB=2cxj | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/S10AD_MOUSE S10AD_MOUSE] Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine.<ref>PMID:12746488</ref> <ref>PMID:17991455</ref> <ref>PMID:11432880</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cx/2cxj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cxj ConSurf].
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<div style="clear:both"></div>
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===3D Solution Structure of S100A13===
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==See Also==
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*[[S100 proteins 3D structures|S100 proteins 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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2CXJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXJ OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Kumar, T K.S.]]
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[[Category: Kumar TKS]]
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[[Category: Vaithiyalingam, S.]]
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[[Category: Vaithiyalingam S]]
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[[Category: Yu, C.]]
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[[Category: Yu C]]
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[[Category: Calcium]]
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[[Category: Fgf]]
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[[Category: Non-classical secretion]]
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[[Category: S100a13]]
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[[Category: Solution]]
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[[Category: Structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 11:52:04 2009''
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Current revision

3D Solution Structure of S100A13

PDB ID 2cxj

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