2q87

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{{Seed}}
 
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[[Image:2q87.png|left|200px]]
 
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==The Crystal Structure of the Human IRp60 Ectodomain==
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The line below this paragraph, containing "STRUCTURE_2q87", creates the "Structure Box" on the page.
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<StructureSection load='2q87' size='340' side='right'caption='[[2q87]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2q87]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Q87 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2q87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q87 OCA], [https://pdbe.org/2q87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2q87 RCSB], [https://www.ebi.ac.uk/pdbsum/2q87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2q87 ProSAT]</span></td></tr>
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{{STRUCTURE_2q87| PDB=2q87 | SCENE= }}
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</table>
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== Function ==
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===The Crystal Structure of the Human IRp60 Ectodomain===
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[https://www.uniprot.org/uniprot/CLM8_HUMAN CLM8_HUMAN] Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.<ref>PMID:10746781</ref> <ref>PMID:16339535</ref> <ref>PMID:9701027</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2Q87 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Q87 OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q8/2q87_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2q87 ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Dimasi, N.]]
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[[Category: Large Structures]]
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[[Category: Marquez, J A.]]
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[[Category: Dimasi N]]
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[[Category: All-beta]]
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[[Category: Marquez JA]]
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[[Category: Cmrf35]]
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[[Category: Ig-superfamily]]
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[[Category: Ig-v]]
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[[Category: Immunoglobulin]]
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[[Category: Inhibitory receptor]]
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[[Category: Irem]]
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[[Category: Irp60]]
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[[Category: Membrane protein]]
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[[Category: Myelo-monocytic cell]]
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[[Category: Natural killer cell ig-like receptor]]
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[[Category: Ncr]]
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[[Category: Negative regulation of leukocyte]]
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[[Category: Negative regulation of natural killer cell]]
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[[Category: Negative regulation of natural mast cell]]
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[[Category: Nkp44-like]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:47:24 2009''
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Current revision

The Crystal Structure of the Human IRp60 Ectodomain

PDB ID 2q87

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Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2q87"
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