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1tqh

From Proteopedia

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{{Seed}}
 
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[[Image:1tqh.png|left|200px]]
 
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<!--
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==Covalent Reaction intermediate Revealed in Crystal Structure of the Geobacillus stearothermophilus Carboxylesterase Est30==
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The line below this paragraph, containing "STRUCTURE_1tqh", creates the "Structure Box" on the page.
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<StructureSection load='1tqh' size='340' side='right'caption='[[1tqh]], [[Resolution|resolution]] 1.63&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1tqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TQH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.63&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4PA:PROPYL+ACETATE'>4PA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1tqh| PDB=1tqh | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tqh OCA], [https://pdbe.org/1tqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tqh RCSB], [https://www.ebi.ac.uk/pdbsum/1tqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tqh ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/EST_GEOSE EST_GEOSE] Involved in the detoxification of xenobiotics. Shows maximal activity with C6 substrates, with gradually decreasing activity from C8 to C12 substrates. No activity for higher chain length substrates acids rather than long-chain ones.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tq/1tqh_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tqh ConSurf].
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<div style="clear:both"></div>
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===Covalent Reaction intermediate Revealed in Crystal Structure of the Geobacillus stearothermophilus Carboxylesterase Est30===
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==See Also==
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*[[Carboxylesterase 3D structures|Carboxylesterase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15327954}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15327954 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15327954}}
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==About this Structure==
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1TQH is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQH OCA].
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==Reference==
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<ref group="xtra">PMID:15327954</ref><references group="xtra"/>
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[[Category: Carboxylesterase]]
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[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Abdelal, A T.]]
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[[Category: Large Structures]]
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[[Category: Ewis, H E.]]
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[[Category: Abdelal AT]]
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[[Category: Harrison, R W.]]
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[[Category: Ewis HE]]
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[[Category: Liu, P.]]
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[[Category: Harrison RW]]
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[[Category: Lu, C D.]]
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[[Category: Liu P]]
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[[Category: Wang, Y F.]]
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[[Category: Lu CD]]
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[[Category: Weber, I T.]]
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[[Category: Wang YF]]
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[[Category: Alpha/beta hydrolase]]
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[[Category: Weber IT]]
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[[Category: Carboxylesterase]]
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[[Category: Tetrahedral intermediate]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:54:54 2009''
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Current revision

Covalent Reaction intermediate Revealed in Crystal Structure of the Geobacillus stearothermophilus Carboxylesterase Est30

PDB ID 1tqh

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