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2hhx

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{{Seed}}
 
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[[Image:2hhx.png|left|200px]]
 
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==O6-methyl-guanine in the polymerase template preinsertion site==
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The line below this paragraph, containing "STRUCTURE_2hhx", creates the "Structure Box" on the page.
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<StructureSection load='2hhx' size='340' side='right'caption='[[2hhx]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2hhx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2HHX FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6OG:6-O-METHYL+GUANOSINE-5-MONOPHOSPHATE'>6OG</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2hhx| PDB=2hhx | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hhx OCA], [https://pdbe.org/2hhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2hhx RCSB], [https://www.ebi.ac.uk/pdbsum/2hhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2hhx ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5KWC1_GEOKA Q5KWC1_GEOKA]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hh/2hhx_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2hhx ConSurf].
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<div style="clear:both"></div>
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===O6-methyl-guanine in the polymerase template preinsertion site===
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_17179038}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 17179038 is the PubMed ID number.
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{{ABSTRACT_PUBMED_17179038}}
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==About this Structure==
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2HHX is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HHX OCA].
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==Reference==
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<ref group="xtra">PMID:17179038</ref><references group="xtra"/>
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[[Category: DNA-directed DNA polymerase]]
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[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Beese, L S.]]
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[[Category: Large Structures]]
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[[Category: Forsberg, L J.]]
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[[Category: Beese LS]]
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[[Category: Warren, J J.]]
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[[Category: Forsberg LJ]]
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[[Category: Dna polymerase i]]
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[[Category: Warren JJ]]
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[[Category: Dna replication]]
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[[Category: Klenow fragment]]
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[[Category: O6-methyl-guanine]]
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[[Category: Protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:00:46 2009''
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Current revision

O6-methyl-guanine in the polymerase template preinsertion site

PDB ID 2hhx

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