1buj

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{{Seed}}
 
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[[Image:1buj.png|left|200px]]
 
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==STRUCTURE OF BINASE IN SOLUTION==
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The line below this paragraph, containing "STRUCTURE_1buj", creates the "Structure Box" on the page.
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<StructureSection load='1buj' size='340' side='right'caption='[[1buj]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1buj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BUJ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1buj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1buj OCA], [https://pdbe.org/1buj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1buj RCSB], [https://www.ebi.ac.uk/pdbsum/1buj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1buj ProSAT]</span></td></tr>
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{{STRUCTURE_1buj| PDB=1buj | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RN_BACIN RN_BACIN] This is a purine-specific ribonuclease.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bu/1buj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1buj ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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We present the spatial structure of binase, a small extracellular ribonuclease, derived from 1H-NMR* data in aqueous solution. The total of 20 structures were obtained via torsion angle dynamics using DYANA program with experimental NOE and hydrogen bond distance constraints and phi and chi1 dihedral angle constraints. The final structures were energy minimised with ECEPP/2 potential in FANTOM program. Binase consists of three alpha-helices in N-terminal part (residues 6-16, 26-32 and 41-44), five-stranded antiparallel beta-sheet in C-terminal part (residues 51-55, 70-75, 86-90, 94-99 and 104-108) and two-stranded parallel beta-sheet (residues 22-24 and 49-51). Three loops (residues 36-39, 56-67 and 76-83), which play significant role in biological functioning of binase, are flexible in solution. The differences between binase and barnase spatial structures in solution explain the differences in thermostability of binase, barnase and their hybrids.
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===STRUCTURE OF BINASE IN SOLUTION===
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Three-dimensional structure of binase in solution.,Reibarkh MYa, Nolde DE, Vasilieva LI, Bocharov EV, Shulga AA, Kirpichnikov MP, Arseniev AS FEBS Lett. 1998 Jul 17;431(2):250-4. PMID:9708913<ref>PMID:9708913</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1buj" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_9708913}}, adds the Publication Abstract to the page
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9708913 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_9708913}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1BUJ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_intermedius Bacillus intermedius]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BUJ OCA].
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==Reference==
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<ref group="xtra">PMID:9708913</ref><references group="xtra"/>
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[[Category: Bacillus intermedius]]
[[Category: Bacillus intermedius]]
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[[Category: Arseniev, A S.]]
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[[Category: Large Structures]]
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[[Category: Nolde, D E.]]
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[[Category: Arseniev AS]]
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[[Category: Reibarkh, M Y.]]
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[[Category: Nolde DE]]
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[[Category: Vasilieva, L I.]]
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[[Category: Reibarkh MY]]
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[[Category: Microbial ribonuclease]]
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[[Category: Vasilieva LI]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:28:47 2009''
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Current revision

STRUCTURE OF BINASE IN SOLUTION

PDB ID 1buj

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