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1c0m

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{{Seed}}
 
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[[Image:1c0m.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF RSV TWO-DOMAIN INTEGRASE==
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The line below this paragraph, containing "STRUCTURE_1c0m", creates the "Structure Box" on the page.
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<StructureSection load='1c0m' size='340' side='right'caption='[[1c0m]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1c0m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C0M FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c0m OCA], [https://pdbe.org/1c0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c0m RCSB], [https://www.ebi.ac.uk/pdbsum/1c0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c0m ProSAT]</span></td></tr>
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{{STRUCTURE_1c0m| PDB=1c0m | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/POL_RSVP POL_RSVP] Capsid protein p27 forms the spherical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity). The aspartyl protease mediates proteolytic cleavages of Gag and Gag-Pol polyproteins during or shortly after the release of the virion from the plasma membrane. Cleavages take place as an ordered, step-wise cascade to yield mature proteins. This process is called maturation. Displays maximal activity during the budding process just prior to particle release from the cell (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c0/1c0m_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c0m ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF RSV TWO-DOMAIN INTEGRASE===
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==See Also==
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*[[Retroviral integrase 3D structures|Retroviral integrase 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10669607}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 10669607 is the PubMed ID number.
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-->
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{{ABSTRACT_PUBMED_10669607}}
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==About this Structure==
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1C0M is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C0M OCA].
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==Reference==
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<ref group="xtra">PMID:10669607</ref><references group="xtra"/>
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[[Category: RNA-directed DNA polymerase]]
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[[Category: Rous sarcoma virus]]
[[Category: Rous sarcoma virus]]
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[[Category: Bushman, F D.]]
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[[Category: Bushman FD]]
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[[Category: Hyde, C C.]]
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[[Category: Hyde CC]]
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[[Category: Mueser, T C.]]
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[[Category: Mueser TC]]
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[[Category: Yang, Z N.]]
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[[Category: Yang Z-N]]
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[[Category: Hiv]]
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[[Category: Integrase]]
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[[Category: Protein structure]]
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[[Category: Rous sarcoma virus]]
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[[Category: Transferase]]
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[[Category: X-ray crystallography]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 13:44:19 2009''
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Current revision

CRYSTAL STRUCTURE OF RSV TWO-DOMAIN INTEGRASE

PDB ID 1c0m

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