1mj3
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1mj3.png|left|200px]] | ||
- | + | ==Crystal Structure Analysis of rat enoyl-CoA hydratase in complex with hexadienoyl-CoA== | |
- | + | <StructureSection load='1mj3' size='340' side='right'caption='[[1mj3]], [[Resolution|resolution]] 2.10Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1mj3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MJ3 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
- | --> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HXC:HEXANOYL-COENZYME+A'>HXC</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mj3 OCA], [https://pdbe.org/1mj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mj3 RCSB], [https://www.ebi.ac.uk/pdbsum/1mj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mj3 ProSAT]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/ECHM_RAT ECHM_RAT] Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mj/1mj3_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mj3 ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | === | + | ==See Also== |
- | + | *[[Enoyl-CoA hydratase|Enoyl-CoA hydratase]] | |
- | + | *[[Enoyl-CoA hydratase 3D structures|Enoyl-CoA hydratase 3D structures]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | [[Category: Large Structures]] | |
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- | < | + | |
- | [[Category: | + | |
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
- | [[Category: Bell | + | [[Category: Bell AF]] |
- | [[Category: Feng | + | [[Category: Feng Y]] |
- | [[Category: Hofstein | + | [[Category: Hofstein HA]] |
- | [[Category: Kisker | + | [[Category: Kisker C]] |
- | [[Category: Parikh | + | [[Category: Parikh S]] |
- | [[Category: Rudolph | + | [[Category: Rudolph MJ]] |
- | [[Category: Tonge | + | [[Category: Tonge PJ]] |
- | [[Category: Wu | + | [[Category: Wu J]] |
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Current revision
Crystal Structure Analysis of rat enoyl-CoA hydratase in complex with hexadienoyl-CoA
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Categories: Large Structures | Rattus norvegicus | Bell AF | Feng Y | Hofstein HA | Kisker C | Parikh S | Rudolph MJ | Tonge PJ | Wu J