This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2a1d

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:23, 20 March 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2a1d.png|left|200px]]
 
-
<!--
+
==Staphylocoagulase bound to bovine thrombin==
-
The line below this paragraph, containing "STRUCTURE_2a1d", creates the "Structure Box" on the page.
+
<StructureSection load='2a1d' size='340' side='right'caption='[[2a1d]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2a1d]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A1D FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0G6:D-PHENYLALANYL-N-[(2S,3S)-6-{[AMINO(IMINIO)METHYL]AMINO}-1-CHLORO-2-HYDROXYHEXAN-3-YL]-L-PROLINAMIDE'>0G6</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-
{{STRUCTURE_2a1d| PDB=2a1d | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a1d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a1d OCA], [https://pdbe.org/2a1d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a1d RCSB], [https://www.ebi.ac.uk/pdbsum/2a1d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a1d ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/THRB_BOVIN THRB_BOVIN] Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a1/2a1d_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a1d ConSurf].
 +
<div style="clear:both"></div>
-
===Staphylocoagulase bound to bovine thrombin===
+
==See Also==
-
 
+
*[[Thrombin 3D Structures|Thrombin 3D Structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_16230338}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 16230338 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_16230338}}
+
-
 
+
-
==About this Structure==
+
-
2A1D is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A1D OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:16230338</ref><references group="xtra"/>
+
[[Category: Bos taurus]]
[[Category: Bos taurus]]
 +
[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
-
[[Category: Thrombin]]
+
[[Category: Bock PE]]
-
[[Category: Bock, P E.]]
+
[[Category: Bode W]]
-
[[Category: Bode, W.]]
+
[[Category: Friedrich R]]
-
[[Category: Friedrich, R.]]
+
[[Category: Fuentes-Prior P]]
-
[[Category: Fuentes-Prior, P.]]
+
[[Category: Kawabata S]]
-
[[Category: Kawabata, S.]]
+
[[Category: Panizzi P]]
-
[[Category: Panizzi, P.]]
+
-
[[Category: Protein-protein complex]]
+
-
[[Category: Prothrombin activator]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:05:58 2009''
+

Current revision

Staphylocoagulase bound to bovine thrombin

PDB ID 2a1d

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2a1d"
Personal tools