1r1n

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:40, 25 December 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1r1n.png|left|200px]]
 
-
<!--
+
==Tri-nuclear oxo-iron clusters in the ferric binding protein from N. gonorrhoeae==
-
The line below this paragraph, containing "STRUCTURE_1r1n", creates the "Structure Box" on the page.
+
<StructureSection load='1r1n' size='340' side='right'caption='[[1r1n]], [[Resolution|resolution]] 1.74&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1r1n]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R1N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R1N FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CN1:OXO-IRON+CLUSTER+2'>CN1</scene>, <scene name='pdbligand=CNB:OXO-IRON+CLUSTER+1'>CNB</scene>, <scene name='pdbligand=CNF:OXO-IRON+CLUSTER+3'>CNF</scene></td></tr>
-
{{STRUCTURE_1r1n| PDB=1r1n | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r1n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r1n OCA], [https://pdbe.org/1r1n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r1n RCSB], [https://www.ebi.ac.uk/pdbsum/1r1n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r1n ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/FBP_NEIGO FBP_NEIGO] This protein may be a central component in the iron-acquisition system.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/1r1n_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r1n ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
We report a set of three 1.8-1.9 A resolution X-ray crystal structures of Neisseria gonorrhoeae Fbp (ferric-ion binding protein): (i) open-cleft apo-Fbp containing bound phosphate, (ii) open-cleft mono-Fe Fbp capped by nitrilotriacetate, and (iii) open-cleft trinuclear oxo-iron Fbp, the first structure of an iron-cluster adduct of a transferrin. The nine independent molecules in the unit cells provide 'snapshots' of the versatile dynamic structural roles of the conserved dityrosyl iron-binding motif (Tyr195-Tyr196) which control the capture and, possibly, processing of iron. These findings have implications for understanding bacterial iron acquisition and dissimilation, and organic/mineral interfaces.
-
===Tri-nuclear oxo-iron clusters in the ferric binding protein from N. gonorrhoeae===
+
Oxo-iron clusters in a bacterial iron-trafficking protein: new roles for a conserved motif.,Zhu H, Alexeev D, Hunter DJ, Campopiano DJ, Sadler PJ Biochem J. 2003 Nov 15;376(Pt 1):35-41. PMID:13129433<ref>PMID:13129433</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 1r1n" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_13129433}}, adds the Publication Abstract to the page
+
*[[Ferric-binding protein|Ferric-binding protein]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 13129433 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_13129433}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
1R1N is a 9 chains structure of sequences from [http://en.wikipedia.org/wiki/Neisseria_gonorrhoeae Neisseria gonorrhoeae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R1N OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:13129433</ref><references group="xtra"/>
+
[[Category: Neisseria gonorrhoeae]]
[[Category: Neisseria gonorrhoeae]]
-
[[Category: Alexeev, D.]]
+
[[Category: Alexeev D]]
-
[[Category: Campopiano, D J.]]
+
[[Category: Campopiano DJ]]
-
[[Category: Hunter, D J.]]
+
[[Category: Hunter DJ]]
-
[[Category: Sadler, P J.]]
+
[[Category: Sadler PJ]]
-
[[Category: Zhu, H.]]
+
[[Category: Zhu H]]
-
[[Category: Iron binding protein]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:16:58 2009''
+

Current revision

Tri-nuclear oxo-iron clusters in the ferric binding protein from N. gonorrhoeae

PDB ID 1r1n

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1r1n"
Personal tools