1ra5

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{{Seed}}
 
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[[Image:1ra5.png|left|200px]]
 
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==Bacterial cytosine deaminase D314A mutant bound to 5-fluoro-4-(S)-hydroxyl-3,4-dihydropyrimidine.==
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The line below this paragraph, containing "STRUCTURE_1ra5", creates the "Structure Box" on the page.
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<StructureSection load='1ra5' size='340' side='right'caption='[[1ra5]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ra5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RA5 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FPY:(4S)-5-FLUORO-4-HYDROXY-3,4-DIHYDROPYRIMIDIN-2(1H)-ONE'>FPY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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{{STRUCTURE_1ra5| PDB=1ra5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ra5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ra5 OCA], [https://pdbe.org/1ra5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ra5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ra5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ra5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CODA_ECOLI CODA_ECOLI]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ra/1ra5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ra5 ConSurf].
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<div style="clear:both"></div>
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===Bacterial cytosine deaminase D314A mutant bound to 5-fluoro-4-(S)-hydroxyl-3,4-dihydropyrimidine.===
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==See Also==
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*[[Deaminase 3D structures|Deaminase 3D structures]]
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 15381761 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15381761}}
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==About this Structure==
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1RA5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RA5 OCA].
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==Reference==
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<ref group="xtra">PMID:15381761</ref><references group="xtra"/>
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[[Category: Cytosine deaminase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Black, M E.]]
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[[Category: Large Structures]]
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[[Category: Ireton, G C.]]
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[[Category: Black ME]]
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[[Category: Mahan, S D.]]
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[[Category: Ireton GC]]
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[[Category: Stoddard, B L.]]
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[[Category: Mahan SD]]
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[[Category: Alpha-beta barrel]]
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[[Category: Stoddard BL]]
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[[Category: Conformational change]]
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[[Category: Cytosine deaminase]]
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[[Category: D314a mutant]]
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[[Category: Hexamer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:18:28 2009''
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Current revision

Bacterial cytosine deaminase D314A mutant bound to 5-fluoro-4-(S)-hydroxyl-3,4-dihydropyrimidine.

PDB ID 1ra5

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OCA

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