2jal

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:13, 6 November 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2jal.png|left|200px]]
 
-
<!--
+
==Beta-glucosidase from Thermotoga maritima in complex with cyclophellitol==
-
The line below this paragraph, containing "STRUCTURE_2jal", creates the "Structure Box" on the page.
+
<StructureSection load='2jal' size='340' side='right'caption='[[2jal]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2jal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JAL FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=YLL:(1R,2S,3S,4S,5R,6R)-6-(HYDROXYMETHYL)CYCLOHEXANE-1,2,3,4,5-PENTOL'>YLL</scene></td></tr>
-
{{STRUCTURE_2jal| PDB=2jal | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jal OCA], [https://pdbe.org/2jal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jal RCSB], [https://www.ebi.ac.uk/pdbsum/2jal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jal ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BGLA_THEMA BGLA_THEMA]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2jal_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jal ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
The structural basis for beta-glucosidase inhibition by cyclophellitol is demonstrated using X-ray crystallography, enzyme kinetics and mass spectrometry.
-
===BETA-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH CYCLOPHELLITOL===
+
Structural basis for cyclophellitol inhibition of a beta-glucosidase.,Gloster TM, Madsen R, Davies GJ Org Biomol Chem. 2007 Feb 7;5(3):444-6. Epub 2006 Dec 14. PMID:17252125<ref>PMID:17252125</ref>
 +
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 +
</div>
 +
<div class="pdbe-citations 2jal" style="background-color:#fffaf0;"></div>
-
<!--
+
==See Also==
-
The line below this paragraph, {{ABSTRACT_PUBMED_17252125}}, adds the Publication Abstract to the page
+
*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 17252125 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_17252125}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
2JAL is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAL OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:17252125</ref><references group="xtra"/>
+
-
[[Category: Beta-glucosidase]]
+
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
-
[[Category: Davies, G J.]]
+
[[Category: Davies GJ]]
-
[[Category: Gloster, T M.]]
+
[[Category: Gloster TM]]
-
[[Category: Madsen, R.]]
+
[[Category: Madsen R]]
-
[[Category: Carbohydrate metabolism]]
+
-
[[Category: Cellulose degradation]]
+
-
[[Category: Covalent]]
+
-
[[Category: Family 1]]
+
-
[[Category: Glycosidase]]
+
-
[[Category: Glycoside hydrolase]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Polysaccharide degradation]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:23:48 2009''
+

Current revision

Beta-glucosidase from Thermotoga maritima in complex with cyclophellitol

PDB ID 2jal

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools