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1ptm
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:1ptm.png|left|200px]] | ||
| - | + | ==Crystal structure of E.coli PdxA== | |
| - | + | <StructureSection load='1ptm' size='340' side='right'caption='[[1ptm]], [[Resolution|resolution]] 1.96Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1ptm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PTM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ptm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ptm OCA], [https://pdbe.org/1ptm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ptm RCSB], [https://www.ebi.ac.uk/pdbsum/1ptm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ptm ProSAT], [https://www.topsan.org/Proteins/BSGI/1ptm TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/PDXA_ECOLI PDXA_ECOLI] Catalyzes the NAD(P)-dependent oxidation of 4-(phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).[REFERENCE:5]<ref>PMID:15026039</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pt/1ptm_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | == | + | </jmolCheckbox> |
| - | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ptm ConSurf]. | |
| - | + | <div style="clear:both"></div> | |
| - | == | + | == References == |
| - | < | + | <references/> |
| - | [[ | + | __TOC__ |
| + | </StructureSection> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Banks | + | [[Category: Banks J]] |
| - | [[Category: Cane | + | [[Category: Cane DE]] |
| - | [[Category: Cygler | + | [[Category: Cygler M]] |
| - | [[Category: Li | + | [[Category: Li Y]] |
| - | [[Category: Matte | + | [[Category: Matte A]] |
| - | [[Category: Sivaraman | + | [[Category: Sivaraman J]] |
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Current revision
Crystal structure of E.coli PdxA
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Categories: Escherichia coli | Large Structures | Banks J | Cane DE | Cygler M | Li Y | Matte A | Sivaraman J

