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2pgi

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{{Seed}}
 
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[[Image:2pgi.png|left|200px]]
 
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==THE CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE-AN ENZYME WITH AUTOCRINE MOTILITY FACTOR ACTIVITY IN TUMOR CELLS==
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The line below this paragraph, containing "STRUCTURE_2pgi", creates the "Structure Box" on the page.
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<StructureSection load='2pgi' size='340' side='right'caption='[[2pgi]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2pgi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. The May 2007 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Aconitase and Iron Regulatory Protein 1'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2007_5 10.2210/rcsb_pdb/mom_2007_5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PGI FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pgi OCA], [https://pdbe.org/2pgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pgi RCSB], [https://www.ebi.ac.uk/pdbsum/2pgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pgi ProSAT]</span></td></tr>
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{{STRUCTURE_2pgi| PDB=2pgi | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/G6PI2_GEOSE G6PI2_GEOSE] Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.[HAMAP-Rule:MF_00473]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pg/2pgi_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2pgi ConSurf].
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<div style="clear:both"></div>
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===THE CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE-AN ENZYME WITH AUTOCRINE MOTILITY FACTOR ACTIVITY IN TUMOR CELLS===
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==See Also==
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*[[Phosphoglucose isomerase 3D structures|Phosphoglucose isomerase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10318897}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10318897 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10318897}}
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==About this Structure==
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2PGI is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. The May 2007 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Aconitase and Iron Regulatory Protein 1'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2007_5 10.2210/rcsb_pdb/mom_2007_5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PGI OCA].
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==Reference==
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<ref group="xtra">PMID:10318897</ref><references group="xtra"/>
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[[Category: Aconitase and Iron Regulatory Protein 1]]
[[Category: Aconitase and Iron Regulatory Protein 1]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
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[[Category: Glucose-6-phosphate isomerase]]
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[[Category: Large Structures]]
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[[Category: Chen, W S.]]
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[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Chou, C C.]]
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[[Category: Chen W-S]]
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[[Category: Hsiao, C D.]]
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[[Category: Chou C-C]]
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[[Category: Meng, M.]]
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[[Category: Hsiao C-D]]
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[[Category: Sun, Y J.]]
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[[Category: Meng M]]
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[[Category: Autocrinefactor]]
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[[Category: Sun Y-J]]
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[[Category: Crystallography]]
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[[Category: Glycolysis]]
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[[Category: Motility]]
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[[Category: Neuroleukin]]
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[[Category: Phosphoglucose isomerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:41:27 2009''
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Current revision

THE CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE-AN ENZYME WITH AUTOCRINE MOTILITY FACTOR ACTIVITY IN TUMOR CELLS

PDB ID 2pgi

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