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1k37

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{{Seed}}
 
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[[Image:1k37.png|left|200px]]
 
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<!--
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==NMR Structure of human Epiregulin==
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The line below this paragraph, containing "STRUCTURE_1k37", creates the "Structure Box" on the page.
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<StructureSection load='1k37' size='340' side='right'caption='[[1k37]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1k37]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K37 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K37 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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-->
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k37 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k37 OCA], [https://pdbe.org/1k37 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k37 RCSB], [https://www.ebi.ac.uk/pdbsum/1k37 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k37 ProSAT]</span></td></tr>
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{{STRUCTURE_1k37| PDB=1k37 | SCENE= }}
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</table>
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== Function ==
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===NMR Structure of human Epiregulin===
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[https://www.uniprot.org/uniprot/EREG_HUMAN EREG_HUMAN] Ligand of the EGF receptor/EGFR and ERBB4. May be a mediator of localized cell proliferation. As a mitogen it may stimulate cell proliferation and/or angiogenesis.<ref>PMID:9419975</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_14572630}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 14572630 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k3/1k37_consurf.spt"</scriptWhenChecked>
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-->
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_14572630}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k37 ConSurf].
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1K37 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K37 OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:14572630</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Aizawa, T.]]
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[[Category: Large Structures]]
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[[Category: Kawano, K.]]
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[[Category: Aizawa T]]
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[[Category: Miura, K.]]
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[[Category: Kawano K]]
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[[Category: Miyamoto, K.]]
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[[Category: Miura K]]
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[[Category: Sato, K.]]
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[[Category: Miyamoto K]]
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[[Category: Tada, M.]]
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[[Category: Sato K]]
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[[Category: Egf-like fold]]
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[[Category: Tada M]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 14:41:52 2009''
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Current revision

NMR Structure of human Epiregulin

PDB ID 1k37

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