2jam

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:40, 13 December 2023) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2jam.png|left|200px]]
 
-
<!--
+
==Crystal structure of human calmodulin-dependent protein kinase I G==
-
The line below this paragraph, containing "STRUCTURE_2jam", creates the "Structure Box" on the page.
+
<StructureSection load='2jam' size='340' side='right'caption='[[2jam]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2jam]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JAM FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=J60:5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE'>J60</scene></td></tr>
-
{{STRUCTURE_2jam| PDB=2jam | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jam OCA], [https://pdbe.org/2jam PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jam RCSB], [https://www.ebi.ac.uk/pdbsum/2jam PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jam ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KCC1G_HUMAN KCC1G_HUMAN] Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1 (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ja/2jam_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jam ConSurf].
 +
<div style="clear:both"></div>
-
===CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE I G===
+
==See Also==
-
 
+
*[[Calcium/calmodulin dependent protein kinase 3D structures|Calcium/calmodulin dependent protein kinase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2JAM is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JAM OCA].
+
-
[[Category: Calcium/calmodulin-dependent protein kinase]]
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Bullock, A.]]
+
[[Category: Unidentified]]
-
[[Category: Bunkoczi, G.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Debreczeni, J E.]]
+
[[Category: Bullock A]]
-
[[Category: Delft, F Von.]]
+
[[Category: Bunkoczi G]]
-
[[Category: Edwards, A.]]
+
[[Category: Debreczeni JE]]
-
[[Category: Keates, T.]]
+
[[Category: Edwards A]]
-
[[Category: Knapp, S.]]
+
[[Category: Keates T]]
-
[[Category: Niesen, F H.]]
+
[[Category: Knapp S]]
-
[[Category: Pike, A C.W.]]
+
[[Category: Niesen FH]]
-
[[Category: Salah, E.]]
+
[[Category: Pike ACW]]
-
[[Category: Shrestha, L.]]
+
[[Category: Salah E]]
-
[[Category: Smee, C.]]
+
[[Category: Shrestha L]]
-
[[Category: Sobott, F.]]
+
[[Category: Smee C]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Sobott F]]
-
[[Category: Turnbull, A.]]
+
[[Category: Sundstrom M]]
-
[[Category: Weigelt, J.]]
+
[[Category: Turnbull A]]
-
[[Category: Allosteric enzyme]]
+
[[Category: Weigelt J]]
-
[[Category: Alternative splicing]]
+
[[Category: Von Delft F]]
-
[[Category: Atp-binding]]
+
-
[[Category: Calmodulin binding]]
+
-
[[Category: Calmodulin-binding]]
+
-
[[Category: Golgi apparatus]]
+
-
[[Category: Kinase]]
+
-
[[Category: Lipoprotein]]
+
-
[[Category: Membrane]]
+
-
[[Category: Nucleotide binding]]
+
-
[[Category: Nucleotide-binding]]
+
-
[[Category: Phosphorylation]]
+
-
[[Category: Polymorphism]]
+
-
[[Category: Prenylation]]
+
-
[[Category: Protein serine/threonine kinase]]
+
-
[[Category: Serine/threonine-protein kinase]]
+
-
[[Category: Transferase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:08:36 2009''
+

Current revision

Crystal structure of human calmodulin-dependent protein kinase I G

PDB ID 2jam

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2jam"
Personal tools