1l8f

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{{Seed}}
 
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[[Image:1l8f.png|left|200px]]
 
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==Structure of 20K-endoglucanase from Melanocarpus albomyces at 1.8 A==
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The line below this paragraph, containing "STRUCTURE_1l8f", creates the "Structure Box" on the page.
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<StructureSection load='1l8f' size='340' side='right'caption='[[1l8f]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1l8f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L8F FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l8f OCA], [https://pdbe.org/1l8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l8f RCSB], [https://www.ebi.ac.uk/pdbsum/1l8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l8f ProSAT]</span></td></tr>
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{{STRUCTURE_1l8f| PDB=1l8f | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8J0K8_MELAO Q8J0K8_MELAO]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l8/1l8f_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l8f ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of the 20K endoglucanase from the thermophilic fungus Melanocarpus albomyces (Ma20k) has been determined. The structure was refined to 1.8 A resolution using data obtained at 120 K. Ma20k belongs to glycoside hydrolase family 45. The three-dimensional structures of endoglucanase V (EGV) from the fungus Humicola insolens and of an endoglucanase from H. grisea var. thermoidea have previously been determined. The overall structure of Ma20k consists of a six-stranded beta-barrel domain similar to that found previously in family 45 endoglucanases. The flexible loop between strands V and VI, which was disordered in the uncomplexed structures of the Humicola endoglucanases but was ordered in complexed structures of EGV, is found to be well ordered in the native structure of Ma20k. The structure of Ma20k allows comparison between thermophilic and mesophilic proteins of family 45 and different principles for thermostability are discussed.
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===Structure of 20K-endoglucanase from Melanocarpus albomyces at 1.8 A===
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Structure of 20K endoglucanase from Melanocarpus albomyces at 1.8 A resolution.,Valjakka J, Rouvinen J Acta Crystallogr D Biol Crystallogr. 2003 Apr;59(Pt 4):765-8. Epub 2003, Mar 25. PMID:12657806<ref>PMID:12657806</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1l8f" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_12657806}}, adds the Publication Abstract to the page
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*[[Glucanase 3D structures|Glucanase 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12657806 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_12657806}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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1L8F is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L8F OCA].
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==Reference==
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<ref group="xtra">PMID:12657806</ref><references group="xtra"/>
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[[Category: Cellulase]]
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[[Category: Melanocarpus albomyces]]
[[Category: Melanocarpus albomyces]]
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[[Category: Rouvinen, J.]]
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[[Category: Rouvinen J]]
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[[Category: Valjakka, J.]]
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[[Category: Valjakka J]]
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[[Category: Cellulase]]
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[[Category: Endoglucanase]]
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[[Category: Thermophilic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 15:31:33 2009''
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Current revision

Structure of 20K-endoglucanase from Melanocarpus albomyces at 1.8 A

PDB ID 1l8f

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