2a8l

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:11, 14 February 2024) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2a8l.png|left|200px]]
 
-
<!--
+
==Crystal structure of Human Taspase1 (T234A mutant)==
-
The line below this paragraph, containing "STRUCTURE_2a8l", creates the "Structure Box" on the page.
+
<StructureSection load='2a8l' size='340' side='right'caption='[[2a8l]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2a8l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A8L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A8L FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a8l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a8l OCA], [https://pdbe.org/2a8l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a8l RCSB], [https://www.ebi.ac.uk/pdbsum/2a8l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a8l ProSAT]</span></td></tr>
-
{{STRUCTURE_2a8l| PDB=2a8l | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Crystal structure of Human Taspase1 (T234A mutant)===
+
[https://www.uniprot.org/uniprot/TASP1_HUMAN TASP1_HUMAN] Protease involved in MLL processing and, consequently, in the correct expression of the early HOXA gene cluster.
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_16216576}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 16216576 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a8/2a8l_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_16216576}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2a8l ConSurf].
-
2A8L is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A8L OCA].
+
<div style="clear:both"></div>
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:16216576</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Dunn, B M.]]
+
[[Category: Large Structures]]
-
[[Category: Khan, J A.]]
+
[[Category: Dunn BM]]
-
[[Category: Tong, L.]]
+
[[Category: Khan JA]]
-
[[Category: Asparaginase]]
+
[[Category: Tong L]]
-
[[Category: Glycosylasparaginase]]
+
-
[[Category: Leukemia]]
+
-
[[Category: Mll]]
+
-
[[Category: Taspase1]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:13:08 2009''
+

Current revision

Crystal structure of Human Taspase1 (T234A mutant)

PDB ID 2a8l

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2a8l"
Personal tools