Template:STRUCTURE 1r1w

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1r1w, resolution 1.80Å ()

Gene:

MET (Homo sapiens)

Activity:

Transferase, with EC number and 2.7.10.2 2.7.10.1 and 2.7.10.2

Related:

1r0p

Structural annotation:
Resources:	CATH : 1R1Wa02, 1R1Wa01 InterPro : Ipr003659, Ipr014756, Ipr002909, Ipr000719, Ipr008266, Ipr002165, Ipr001627, Ipr001245, Ipr011009 Pfam : PF07714 SCOP : d1r1wa_ UniProt : P08581

Functional annotation:
Cellular component:	membrane fraction integral to membrane membrane integral to plasma membrane basal plasma membrane
Biological process:	multicellular organismal development cell surface receptor linked signal transduction protein amino acid autophosphorylation cell proliferation brain development adult behavior activation of MAPK activity signal transduction protein amino acid phosphorylation hepatocyte growth factor receptor signaling pathway myoblast proliferation muscle development
Molecular function:	transferase activity receptor activity nucleotide binding hepatocyte growth factor receptor activity protein-tyrosine kinase activity kinase activity protein binding protein kinase activity ATP binding

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/Template:STRUCTURE_1r1w"

@@ Line 1: / Line 1: @@
 {{Structure
-|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1r1w]], resolution 1.80&Aring; (<scene name='initialview01'>default scene</scene>)}}}
+|PDB= {{{PDB}}}|SCENE={{{SCENE|}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|[[1r1w]], [[Resolution|resolution]] 1.80&Aring; (<scene name='initialview01'>default scene</scene>)}}}
 |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] </span>
 |GENE= MET ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05058 PTKc_Met_Ron], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=smart00220 S_TKc]</span>
 |RELATEDENTRY=[[1r0p|1r0p]]
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r1w OCA], [http://www.ebi.ac.uk/pdbsum/1r1w PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1r1w RCSB]</span>
+|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1r1w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r1w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1r1w RCSB], [http://www.ebi.ac.uk/pdbsum/1r1w PDBsum]</span>
 |FUNCTION={{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0004872 | text = receptor activity}}{{GO|id=GO:0000166 | text = nucleotide binding}}{{GO|id=GO:0005008 | text = hepatocyte growth factor receptor activity}}{{GO|id=GO:0004713 | text = protein-tyrosine kinase activity}}{{GO|id=GO:0016301 | text = kinase activity}}{{GO|id=GO:0005515 | text = protein binding}}{{GO|id=GO:0004672 | text = protein kinase activity}}{{GO|id=GO:0005524 | text = ATP binding}}
 |PROCESS={{GO|id=GO:0007275 | text = multicellular organismal development}}{{GO|id=GO:0007166 | text = cell surface receptor linked signal transduction}}{{GO|id=GO:0046777 | text = protein amino acid autophosphorylation}}{{GO|id=GO:0008283 | text = cell proliferation}}{{GO|id=GO:0007420 | text = brain development}}{{GO|id=GO:0030534 | text = adult behavior}}{{GO|id=GO:0000187 | text = activation of MAPK activity}}{{GO|id=GO:0007165 | text = signal transduction}}{{GO|id=GO:0006468 | text = protein amino acid phosphorylation}}{{GO|id=GO:0048012 | text = hepatocyte growth factor receptor signaling pathway}}{{GO|id=GO:0051450 | text = myoblast proliferation}}{{GO|id=GO:0007517 | text = muscle development}}
 |COMPONENT={{GO|id=GO:0005624 | text = membrane fraction}}{{GO|id=GO:0016021 | text = integral to membrane}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0005887 | text = integral to plasma membrane}}{{GO|id=GO:0009925 | text = basal plasma membrane}}
 |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1r1wA02 1R1Wa02], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1r1wA01 1R1Wa01]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003659 Ipr003659], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014756 Ipr014756], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002909 Ipr002909], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000719 Ipr000719], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008266 Ipr008266], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002165 Ipr002165], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001627 Ipr001627], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001245 Ipr001245], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR011009 Ipr011009]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF07714 PF07714]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&amp;key=96833 d1r1wa_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P08581 P08581]</span>
-|FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=MET MET]</span>
+|uPDB=1R1W|CONSURF={{!}}-
-|CONSURF={{!}}-
 {{!}} colspan="2" style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;" {{!}} [[Image:Consurf_key_small.gif|center]]
 {{!}}-{{!}} style="background-color:#bac9f7;color:#040d44;vertical-align:top;text-align:left;"

Template:STRUCTURE 1r1w

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