3ble

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:03, 13 March 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3ble.png|left|200px]]
 
-
<!--
+
==Crystal structure of the catalytic domain of LiCMS in complexed with malonate==
-
The line below this paragraph, containing "STRUCTURE_3ble", creates the "Structure Box" on the page.
+
<StructureSection load='3ble' size='340' side='right'caption='[[3ble]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3ble]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leptospira_interrogans Leptospira interrogans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BLE FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_3ble| PDB=3ble | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ble FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ble OCA], [https://pdbe.org/3ble PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ble RCSB], [https://www.ebi.ac.uk/pdbsum/3ble PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ble ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of the catalytic domain of LiCMS in complexed with malonate===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/CIMA_LEPIN CIMA_LEPIN] Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate (PubMed:15292141, PubMed:18498255, PubMed:19351325). Shows strict substrate specificity for pyruvate. Cannot use alpha-ketoisovalerate, alpha-ketobutyrate, alpha-ketoisocaproate, alpha-ketoglutarate or glyoxylate (PubMed:15292141, PubMed:18498255).<ref>PMID:15292141</ref> <ref>PMID:18498255</ref> <ref>PMID:19351325</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_18498255}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 18498255 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bl/3ble_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_18498255}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
3BLE is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Leptospira_interrogans Leptospira interrogans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BLE OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ble ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
<ref group="xtra">PMID:18498255</ref><references group="xtra"/>
+
<references/>
-
[[Category: 2-isopropylmalate synthase]]
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Leptospira interrogans]]
[[Category: Leptospira interrogans]]
-
[[Category: Ma, J.]]
+
[[Category: Ma J]]
-
[[Category: Zhang, P.]]
+
[[Category: Zhang P]]
-
[[Category: Acyltransferase]]
+
-
[[Category: Amino-acid biosynthesis]]
+
-
[[Category: Branched-chain amino acid biosynthesis]]
+
-
[[Category: Leucine biosynthesis]]
+
-
[[Category: Licmsn]]
+
-
[[Category: Substrate specificity]]
+
-
[[Category: Tim barrel]]
+
-
[[Category: Transferase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 16:47:38 2009''
+

Current revision

Crystal structure of the catalytic domain of LiCMS in complexed with malonate

PDB ID 3ble

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3ble"
Personal tools