2jis

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:28, 9 April 2025) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2jis.png|left|200px]]
 
-
<!--
+
==Human cysteine sulfinic acid decarboxylase (CSAD) in complex with PLP.==
-
The line below this paragraph, containing "STRUCTURE_2jis", creates the "Structure Box" on the page.
+
<StructureSection load='2jis' size='340' side='right'caption='[[2jis]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2jis]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JIS FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
-
{{STRUCTURE_2jis| PDB=2jis | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jis OCA], [https://pdbe.org/2jis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jis RCSB], [https://www.ebi.ac.uk/pdbsum/2jis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jis ProSAT]</span></td></tr>
-
 
+
</table>
-
===HUMAN CYSTEINE SULFINIC ACID DECARBOXYLASE (CSAD) IN COMPLEX WITH PLP.===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/CSAD_HUMAN CSAD_HUMAN] Catalyzes the decarboxylation of L-aspartate, 3-sulfino-L-alanine (cysteine sulfinic acid), and L-cysteate to beta-alanine, hypotaurine and taurine, respectively. The preferred substrate is 3-sulfino-L-alanine. Does not exhibit any decarboxylation activity toward glutamate.[UniProtKB:Q9DBE0]
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2JIS is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JIS OCA].
+
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ji/2jis_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jis ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Sulfinoalanine decarboxylase]]
+
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Arrowsmith C]]
-
[[Category: Berg, S Van Den.]]
+
[[Category: Berglund H]]
-
[[Category: Berglund, H.]]
+
[[Category: Busam R]]
-
[[Category: Busam, R.]]
+
[[Category: Collins R]]
-
[[Category: Collins, R.]]
+
[[Category: Dahlgren LG]]
-
[[Category: Dahlgren, L G.]]
+
[[Category: Edwards A]]
-
[[Category: Edwards, A.]]
+
[[Category: Flodin S]]
-
[[Category: Flodin, S.]]
+
[[Category: Flores A]]
-
[[Category: Flores, A.]]
+
[[Category: Graslund S]]
-
[[Category: Graslund, S.]]
+
[[Category: Hallberg BM]]
-
[[Category: Hallberg, B M.]]
+
[[Category: Hammarstrom M]]
-
[[Category: Hammarstrom, M.]]
+
[[Category: Holmberg-Schiavone L]]
-
[[Category: Holmberg-Schiavone, L.]]
+
[[Category: Johansson I]]
-
[[Category: Johansson, I.]]
+
[[Category: Kallas A]]
-
[[Category: Kallas, A.]]
+
[[Category: Karlberg T]]
-
[[Category: Karlberg, T.]]
+
[[Category: Kotenyova T]]
-
[[Category: Kotenyova, T.]]
+
[[Category: Lehtio L]]
-
[[Category: Lehtio, L.]]
+
[[Category: Moche M]]
-
[[Category: Moche, M.]]
+
[[Category: Nordlund P]]
-
[[Category: Nordlund, P.]]
+
[[Category: Nyman T]]
-
[[Category: Nyman, T.]]
+
[[Category: Ogg D]]
-
[[Category: Ogg, D.]]
+
[[Category: Persson C]]
-
[[Category: Persson, C.]]
+
[[Category: Sagemark J]]
-
[[Category: Sagemark, J.]]
+
[[Category: Stenmark P]]
-
[[Category: Sgc, Structural GenomicsConsortium.]]
+
[[Category: Sundstrom M]]
-
[[Category: Stenmark, P.]]
+
[[Category: Thorsell AG]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Tresaugues L]]
-
[[Category: Thorsell, A G.]]
+
[[Category: Weigelt J]]
-
[[Category: Tresaugues, L.]]
+
[[Category: Welin M]]
-
[[Category: Weigelt, J.]]
+
[[Category: Van den Berg S]]
-
[[Category: Welin, M.]]
+
-
[[Category: Alternative splicing]]
+
-
[[Category: Decarboxylase]]
+
-
[[Category: Lyase]]
+
-
[[Category: Pyridoxal phosphate]]
+
-
[[Category: Vitamin b6]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:50:44 2009''
+

Current revision

Human cysteine sulfinic acid decarboxylase (CSAD) in complex with PLP.

PDB ID 2jis

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2jis"
Personal tools