3csr

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{{Seed}}
 
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[[Image:3csr.png|left|200px]]
 
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==Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail==
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The line below this paragraph, containing "STRUCTURE_3csr", creates the "Structure Box" on the page.
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<StructureSection load='3csr' size='340' side='right'caption='[[3csr]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3csr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_phage_phi29 Bacillus phage phi29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CSR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3csr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3csr OCA], [https://pdbe.org/3csr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3csr RCSB], [https://www.ebi.ac.uk/pdbsum/3csr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3csr ProSAT]</span></td></tr>
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{{STRUCTURE_3csr| PDB=3csr | SCENE= }}
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</table>
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== Function ==
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===Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail===
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[https://www.uniprot.org/uniprot/GP13_BPPH2 GP13_BPPH2] May serve as a plug to restrain the highly pressurized packaged genome and thus would be the first virion protein to contact the host cell wall, degrading the peptidoglycan layer and thereby facilitating viral genome entry into the host bacteria. Acts probably as a multifunctional enzyme that degrades N-acetylglucosamine polymers (in vitro) and cleaves the peptide cross-links of the host cell wall. Essential for the tail assembly.<ref>PMID:18394643</ref> <ref>PMID:18606992</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_18606992}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 18606992 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cs/3csr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_18606992}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3csr ConSurf].
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3CSR is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_phage_phi29 Bacillus phage phi29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CSR OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:18606992</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Bacillus phage phi29]]
[[Category: Bacillus phage phi29]]
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[[Category: Rossmann, M G.]]
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[[Category: Large Structures]]
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[[Category: Xiang, Y.]]
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[[Category: Rossmann MG]]
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[[Category: Cell wall]]
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[[Category: Xiang Y]]
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[[Category: Hydrolase]]
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[[Category: Infection]]
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[[Category: Late protein]]
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[[Category: Phi29]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 17:55:08 2009''
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Current revision

Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail

PDB ID 3csr

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