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1hzk

From Proteopedia

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{{Seed}}
 
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[[Image:1hzk.png|left|200px]]
 
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==SOLUTION STRUCTURES OF C-1027 APOPROTEIN AND ITS COMPLEX WITH THE AROMATIZED CHROMOPHORE==
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The line below this paragraph, containing "STRUCTURE_1hzk", creates the "Structure Box" on the page.
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<StructureSection load='1hzk' size='340' side='right'caption='[[1hzk]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1hzk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_globisporus Streptomyces globisporus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HZK FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hzk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzk OCA], [https://pdbe.org/1hzk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hzk RCSB], [https://www.ebi.ac.uk/pdbsum/1hzk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hzk ProSAT]</span></td></tr>
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{{STRUCTURE_1hzk| PDB=1hzk | SCENE= }}
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</table>
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== Function ==
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===SOLUTION STRUCTURES OF C-1027 APOPROTEIN AND ITS COMPLEX WITH THE AROMATIZED CHROMOPHORE===
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[https://www.uniprot.org/uniprot/CAGA_STRGL CAGA_STRGL] Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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<!--
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Check<jmol>
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The line below this paragraph, {{ABSTRACT_PUBMED_11491295}}, adds the Publication Abstract to the page
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 11491295 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/1hzk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_11491295}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hzk ConSurf].
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1HZK is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_globisporus Streptomyces globisporus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZK OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:11491295</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Streptomyces globisporus]]
[[Category: Streptomyces globisporus]]
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[[Category: Fukuda-Ishisaka, S.]]
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[[Category: Fukuda-Ishisaka S]]
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[[Category: Hirama, M.]]
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[[Category: Hirama M]]
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[[Category: Otani, T.]]
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[[Category: Otani T]]
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[[Category: Tanaka, T.]]
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[[Category: Tanaka T]]
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[[Category: Apoprotein]]
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[[Category: C-1027]]
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[[Category: Chromoprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:14:48 2009''
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Current revision

SOLUTION STRUCTURES OF C-1027 APOPROTEIN AND ITS COMPLEX WITH THE AROMATIZED CHROMOPHORE

PDB ID 1hzk

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