2gel

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{{Seed}}
 
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[[Image:2gel.png|left|200px]]
 
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==2.05A crystal structure of Salmonella typhimurium YeaZ, form B==
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The line below this paragraph, containing "STRUCTURE_2gel", creates the "Structure Box" on the page.
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<StructureSection load='2gel' size='340' side='right'caption='[[2gel]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2gel]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GEL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gel OCA], [https://pdbe.org/2gel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gel RCSB], [https://www.ebi.ac.uk/pdbsum/2gel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gel ProSAT]</span></td></tr>
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{{STRUCTURE_2gel| PDB=2gel | SCENE= }}
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</table>
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== Function ==
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===2.05A crystal structure of Salmonella typhimurium YeaZ, form B===
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[https://www.uniprot.org/uniprot/TSAB_SALTY TSAB_SALTY] Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaE; this reaction does not require ATP in vitro. TsaB seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity). Neither binds polyphosphates nor a wide range of nucleotides on its own. Does not show O-sialoglycoprotein endopeptidase activity. Has been identified as the first Gram-negative bacterial RPF (Resuscitation-Promoting Factor) capable of reviving VNC (viable but non-culturable) cells when added externally, but the million-fold lower activity as compared to Gram-positive bacterial RPFs may indicate a lack of physiological relevance.<ref>PMID:16213054</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 16617437 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ge/2gel_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_16617437}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gel ConSurf].
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2GEL is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GEL OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:16617437</ref><references group="xtra"/>
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__TOC__
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[[Category: Salmonella typhimurium]]
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</StructureSection>
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[[Category: Nichols, C E.]]
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[[Category: Large Structures]]
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[[Category: Stammers, D K.]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Actin-like-fold]]
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[[Category: Nichols CE]]
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[[Category: Glycoprotease]]
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[[Category: Stammers DK]]
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[[Category: M22]]
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[[Category: Rpf]]
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[[Category: Yeaz]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:20:43 2009''
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Current revision

2.05A crystal structure of Salmonella typhimurium YeaZ, form B

PDB ID 2gel

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