1rr7
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1rr7.png|left|200px]] | ||
- | + | ==Crystal structure of the Middle Operon Regulator protein of Bacteriophage Mu== | |
- | + | <StructureSection load='1rr7' size='340' side='right'caption='[[1rr7]], [[Resolution|resolution]] 2.20Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1rr7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Mu Escherichia virus Mu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RR7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RR7 FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rr7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rr7 OCA], [https://pdbe.org/1rr7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rr7 RCSB], [https://www.ebi.ac.uk/pdbsum/1rr7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rr7 ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/MOR_BPMU MOR_BPMU] Activator of the Pm promoter, which controls middle genes expression. Activation of Pm allows expression of protein C necessary for late gene expression. In addition to Mor binding, activation of Pm might require the interaction of Mor with the C-terminus of host RNAP subunits RpoA and RpoH.<ref>PMID:2173258</ref> <ref>PMID:8790343</ref> | |
- | + | == Evolutionary Conservation == | |
- | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | + | Check<jmol> | |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rr/1rr7_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | == | + | </jmolCheckbox> |
- | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rr7 ConSurf]. | |
- | + | <div style="clear:both"></div> | |
- | == | + | == References == |
- | < | + | <references/> |
- | [[ | + | __TOC__ |
- | [ | + | </StructureSection> |
- | [ | + | [[Category: Escherichia virus Mu]] |
- | [ | + | [[Category: Large Structures]] |
- | [[ | + | [[Category: Howe MM]] |
- | + | [[Category: Kumaraswami M]] | |
- | + | [[Category: Park HW]] |
Current revision
Crystal structure of the Middle Operon Regulator protein of Bacteriophage Mu
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