2fa9

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(New page: 200px<br /><applet load="2fa9" size="450" color="white" frame="true" align="right" spinBox="true" caption="2fa9, resolution 2.50&Aring;" /> '''The crystal structur...)
Current revision (08:44, 25 October 2023) (edit) (undo)
 
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[[Image:2fa9.gif|left|200px]]<br /><applet load="2fa9" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="2fa9, resolution 2.50&Aring;" />
 
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'''The crystal structure of Sar1[H79G]-GDP provides insight into the coat-controlled GTP hydrolysis in the disassembly of COP II'''<br />
 
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==About this Structure==
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==The crystal structure of Sar1[H79G]-GDP provides insight into the coat-controlled GTP hydrolysis in the disassembly of COP II==
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2FA9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus] with MG, SO4 and GDP as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2FA9 OCA].
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<StructureSection load='2fa9' size='340' side='right'caption='[[2fa9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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[[Category: Cricetulus griseus]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[2fa9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FA9 FirstGlance]. <br>
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[[Category: Bian, C.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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[[Category: Hou, X.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Huang, M.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fa9 OCA], [https://pdbe.org/2fa9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fa9 RCSB], [https://www.ebi.ac.uk/pdbsum/2fa9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fa9 ProSAT]</span></td></tr>
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[[Category: Rao, Y.]]
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</table>
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[[Category: Yuan, C.]]
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== Function ==
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[[Category: GDP]]
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[https://www.uniprot.org/uniprot/SAR1B_CRIGR SAR1B_CRIGR] Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.<ref>PMID:8138575</ref> <ref>PMID:11149932</ref>
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[[Category: MG]]
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== Evolutionary Conservation ==
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[[Category: SO4]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: sar1h79g mutant]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fa/2fa9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fa9 ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 10:27:01 2007''
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==See Also==
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*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Cricetulus griseus]]
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[[Category: Large Structures]]
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[[Category: Bian C]]
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[[Category: Hou X]]
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[[Category: Huang M]]
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[[Category: Rao Y]]
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[[Category: Yuan C]]

Current revision

The crystal structure of Sar1[H79G]-GDP provides insight into the coat-controlled GTP hydrolysis in the disassembly of COP II

PDB ID 2fa9

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