1ypr

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{{Seed}}
 
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[[Image:1ypr.png|left|200px]]
 
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==SACCHAROMYCES CEREVISIAE (YEAST) PROFILIN==
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The line below this paragraph, containing "STRUCTURE_1ypr", creates the "Structure Box" on the page.
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<StructureSection load='1ypr' size='340' side='right'caption='[[1ypr]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ypr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YPR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ypr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ypr OCA], [https://pdbe.org/1ypr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ypr RCSB], [https://www.ebi.ac.uk/pdbsum/1ypr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ypr ProSAT]</span></td></tr>
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{{STRUCTURE_1ypr| PDB=1ypr | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PROF_YEAST PROF_YEAST] Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yp/1ypr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ypr ConSurf].
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<div style="clear:both"></div>
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===SACCHAROMYCES CEREVISIAE (YEAST) PROFILIN===
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==See Also==
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*[[Profilin 3D Structures|Profilin 3D Structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9698363}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9698363 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9698363}}
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==About this Structure==
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1YPR is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YPR OCA].
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==Reference==
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<ref group="xtra">PMID:9698363</ref><references group="xtra"/>
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Almo, S C.]]
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[[Category: Almo SC]]
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[[Category: Eads, J C.]]
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[[Category: Eads JC]]
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[[Category: Mahoney, N M.]]
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[[Category: Mahoney NM]]
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[[Category: Actin-binding protein]]
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[[Category: Cytoskeleton]]
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[[Category: Profilin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:03:52 2009''
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Current revision

SACCHAROMYCES CEREVISIAE (YEAST) PROFILIN

PDB ID 1ypr

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