2iag

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:52, 13 March 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2iag.png|left|200px]]
 
-
<!--
+
==Crystal structure of human prostacyclin synthase==
-
The line below this paragraph, containing "STRUCTURE_2iag", creates the "Structure Box" on the page.
+
<StructureSection load='2iag' size='340' side='right'caption='[[2iag]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2iag]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IAG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IAG FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-
{{STRUCTURE_2iag| PDB=2iag | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2iag FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iag OCA], [https://pdbe.org/2iag PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2iag RCSB], [https://www.ebi.ac.uk/pdbsum/2iag PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2iag ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of human prostacyclin synthase===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/PTGIS_HUMAN PTGIS_HUMAN] Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_17020766}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 17020766 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ia/2iag_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_17020766}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==Disease==
+
</jmolCheckbox>
-
Known disease associated with this structure: Hypertension, essential OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601699 601699]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2iag ConSurf].
-
 
+
<div style="clear:both"></div>
-
==About this Structure==
+
__TOC__
-
2IAG is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IAG OCA].
+
</StructureSection>
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:17020766</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Prostaglandin-I synthase]]
+
[[Category: Large Structures]]
-
[[Category: Chan, N L.]]
+
[[Category: Chan N-L]]
-
[[Category: Chiang, C W.]]
+
[[Category: Chiang C-W]]
-
[[Category: Wang, L H.]]
+
[[Category: Wang L-H]]
-
[[Category: Yeh, H C.]]
+
[[Category: Yeh H-C]]
-
[[Category: Class iii cytochorme p450]]
+
-
[[Category: Cyp8a1]]
+
-
[[Category: Hemoprotein]]
+
-
[[Category: Prostacyclin synthase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:06:19 2009''
+

Current revision

Crystal structure of human prostacyclin synthase

PDB ID 2iag

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2iag"
Personal tools