2ev8

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{{Seed}}
 
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[[Image:2ev8.png|left|200px]]
 
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==Solution structure of the erythroid p55 PDZ domain==
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The line below this paragraph, containing "STRUCTURE_2ev8", creates the "Structure Box" on the page.
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<StructureSection load='2ev8' size='340' side='right'caption='[[2ev8]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2ev8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EV8 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ev8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ev8 OCA], [https://pdbe.org/2ev8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ev8 RCSB], [https://www.ebi.ac.uk/pdbsum/2ev8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ev8 ProSAT]</span></td></tr>
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{{STRUCTURE_2ev8| PDB=2ev8 | SCENE= }}
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</table>
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== Function ==
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===Solution structure of the erythroid p55 PDZ domain===
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[https://www.uniprot.org/uniprot/EM55_HUMAN EM55_HUMAN] Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2EV8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EV8 OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ev/2ev8_consurf.spt"</scriptWhenChecked>
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==Reference==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<ref group="xtra">PMID:16741958</ref><references group="xtra"/>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ev8 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Kohno, T.]]
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[[Category: Large Structures]]
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[[Category: Kusunoki, H.]]
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[[Category: Kohno T]]
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[[Category: Maguk]]
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[[Category: Kusunoki H]]
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[[Category: P55]]
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[[Category: Pdz]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 19:08:18 2009''
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Current revision

Solution structure of the erythroid p55 PDZ domain

PDB ID 2ev8

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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