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1q9j

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{{Seed}}
 
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[[Image:1q9j.png|left|200px]]
 
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==Structure of polyketide synthase associated protein 5 from Mycobacterium tuberculosis==
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The line below this paragraph, containing "STRUCTURE_1q9j", creates the "Structure Box" on the page.
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<StructureSection load='1q9j' size='340' side='right'caption='[[1q9j]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1q9j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q9J FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q9j OCA], [https://pdbe.org/1q9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q9j RCSB], [https://www.ebi.ac.uk/pdbsum/1q9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q9j ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1q9j TOPSAN]</span></td></tr>
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{{STRUCTURE_1q9j| PDB=1q9j | SCENE= }}
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</table>
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== Function ==
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===Structure of polyketide synthase associated protein 5 from Mycobacterium tuberculosis===
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[https://www.uniprot.org/uniprot/PAPA5_MYCTU PAPA5_MYCTU] Catalyzes diesterification of phthiocerol and phthiodiolone with mycocerosic acids, the final step in the phthiocerol and phthiodiolone dimycocerosate esters (PDIM) synthesis. Can directly transfer the mycocerosate bound to the mycocerosic acid synthase (mas) onto the substrate alcohols. Is also able to catalyze acyl transfer using various nucleophiles as acceptors and several acyl-CoA thioesters as donors in vitro; preference is observed for saturated medium chain alcohols and long chain acyl-CoA thioesters.<ref>PMID:15070765</ref> <ref>PMID:15749014</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 15123643 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q9/1q9j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_15123643}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q9j ConSurf].
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1Q9J is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q9J OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:15123643</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Buglino, J.]]
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[[Category: Buglino J]]
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[[Category: Burley, S K.]]
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[[Category: Burley SK]]
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[[Category: Lima, C D.]]
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[[Category: Lima CD]]
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[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
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[[Category: Onwueme KC]]
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[[Category: Onwueme, K C.]]
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[[Category: Quadri LE]]
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[[Category: Quadri, L E.]]
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[[Category: Conjugating enzyme papa5]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: New york structural genomix research consortium]]
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[[Category: Nysgxrc]]
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[[Category: Polyketide synthase associated protein]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:40:26 2009''
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Current revision

Structure of polyketide synthase associated protein 5 from Mycobacterium tuberculosis

PDB ID 1q9j

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