1ka9

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{{Seed}}
 
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[[Image:1ka9.png|left|200px]]
 
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==Imidazole Glycerol Phosphate Synthase==
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The line below this paragraph, containing "STRUCTURE_1ka9", creates the "Structure Box" on the page.
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<StructureSection load='1ka9' size='340' side='right'caption='[[1ka9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ka9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KA9 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ka9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ka9 OCA], [https://pdbe.org/1ka9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ka9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ka9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ka9 ProSAT], [https://www.topsan.org/Proteins/RSGI/1ka9 TOPSAN]</span></td></tr>
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{{STRUCTURE_1ka9| PDB=1ka9 | SCENE= }}
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</table>
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== Function ==
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===Imidazole Glycerol Phosphate Synthase===
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[https://www.uniprot.org/uniprot/HIS5_THET8 HIS5_THET8] IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity).[HAMAP-Rule:MF_00278]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 12417026 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ka/1ka9_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_12417026}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ka9 ConSurf].
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1KA9 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KA9 OCA].
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<div style="clear:both"></div>
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:12417026</ref><references group="xtra"/>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Hirotsu, K.]]
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[[Category: Hirotsu K]]
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[[Category: Miyahara, I.]]
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[[Category: Miyahara I]]
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[[Category: Omi, R.]]
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[[Category: Omi R]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Synthase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:45:57 2009''
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Current revision

Imidazole Glycerol Phosphate Synthase

PDB ID 1ka9

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