2nnl

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:54, 25 October 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2nnl.png|left|200px]]
 
-
<!--
+
==Binding of two substrate analogue molecules to dihydroflavonol-4-reductase alters the functional geometry of the catalytic site==
-
The line below this paragraph, containing "STRUCTURE_2nnl", creates the "Structure Box" on the page.
+
<StructureSection load='2nnl' size='340' side='right'caption='[[2nnl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2nnl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NNL FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ERD:(2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE'>ERD</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
-
{{STRUCTURE_2nnl| PDB=2nnl | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nnl OCA], [https://pdbe.org/2nnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nnl RCSB], [https://www.ebi.ac.uk/pdbsum/2nnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nnl ProSAT]</span></td></tr>
-
 
+
</table>
-
===Binding of two substrate analogue molecules to dihydroflavonol-4-reductase alters the functional geometry of the catalytic site===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/DFRA_VITVI DFRA_VITVI] Bifunctional enzyme involved in flavonoid metabolism.[UniProtKB:Q9XES5]
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2NNL is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Vitis_vinifera Vitis vinifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NNL OCA].
+
Check<jmol>
-
[[Category: Dihydrokaempferol 4-reductase]]
+
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nn/2nnl_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nnl ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Vitis vinifera]]
[[Category: Vitis vinifera]]
-
[[Category: Estaintot, B Langlois D.]]
+
[[Category: Gallois B]]
-
[[Category: Gallois, B.]]
+
[[Category: Granier T]]
-
[[Category: Granier, T.]]
+
[[Category: Langlois D'Estaintot B]]
-
[[Category: Petit, P.]]
+
[[Category: Petit P]]
-
[[Category: Oxidoreductase]]
+
-
[[Category: Rossmann fold]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:39:58 2009''
+

Current revision

Binding of two substrate analogue molecules to dihydroflavonol-4-reductase alters the functional geometry of the catalytic site

PDB ID 2nnl

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2nnl"
Personal tools