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2fyf

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(New page: 200px<br /><applet load="2fyf" size="450" color="white" frame="true" align="right" spinBox="true" caption="2fyf, resolution 1.5&Aring;" /> '''Structure of a putati...)
Current revision (09:25, 14 February 2024) (edit) (undo)
 
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[[Image:2fyf.jpg|left|200px]]<br /><applet load="2fyf" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="2fyf, resolution 1.5&Aring;" />
 
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'''Structure of a putative phosphoserine aminotransferase from Mycobacterium Tuberculosis'''<br />
 
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==About this Structure==
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==Structure of a putative phosphoserine aminotransferase from Mycobacterium Tuberculosis==
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2FYF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with SO4, PC4, PLP and GOL as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phosphoserine_transaminase Phosphoserine transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.52 2.6.1.52] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2FYF OCA].
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<StructureSection load='2fyf' size='340' side='right'caption='[[2fyf]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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[[Category: Mycobacterium tuberculosis]]
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== Structural highlights ==
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[[Category: Phosphoserine transaminase]]
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<table><tr><td colspan='2'>[[2fyf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FYF FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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[[Category: Baker, E.N.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PC4:TETRACHLOROPLATINATE(II)'>PC4</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Coulibaly, F.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fyf OCA], [https://pdbe.org/2fyf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fyf RCSB], [https://www.ebi.ac.uk/pdbsum/2fyf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fyf ProSAT]</span></td></tr>
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[[Category: Lassalle, E.]]
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</table>
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[[Category: XMTB, Mycobacterium.Tuberculosis.Structural.Proteomics.Project.]]
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== Function ==
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[[Category: GOL]]
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[https://www.uniprot.org/uniprot/SERC_MYCTU SERC_MYCTU] Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine (By similarity).[HAMAP-Rule:MF_00160]
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[[Category: PC4]]
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== Evolutionary Conservation ==
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[[Category: PLP]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: SO4]]
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Check<jmol>
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[[Category: dimer]]
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<jmolCheckbox>
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[[Category: mycobacterium tuberculosis structural proteomics project]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fy/2fyf_consurf.spt"</scriptWhenChecked>
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[[Category: plp-dependent enzyme]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: structural genomics]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: xmtb]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fyf ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 10:50:24 2007''
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==See Also==
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*[[Phosphoserine aminotransferase|Phosphoserine aminotransferase]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Baker EN]]
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[[Category: Coulibaly F]]
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[[Category: Lassalle E]]

Current revision

Structure of a putative phosphoserine aminotransferase from Mycobacterium Tuberculosis

PDB ID 2fyf

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