4tmy

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{{Seed}}
 
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[[Image:4tmy.png|left|200px]]
 
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==CHEY FROM THERMOTOGA MARITIMA (MG-IV)==
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The line below this paragraph, containing "STRUCTURE_4tmy", creates the "Structure Box" on the page.
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<StructureSection load='4tmy' size='340' side='right'caption='[[4tmy]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[4tmy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TMY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TMY FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_4tmy| PDB=4tmy | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tmy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tmy OCA], [https://pdbe.org/4tmy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tmy RCSB], [https://www.ebi.ac.uk/pdbsum/4tmy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tmy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CHEY_THEMA CHEY_THEMA] Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheY seems to regulate the clockwise (CW) rotation (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tm/4tmy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=4tmy ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of CheY protein from Thermotoga maritima has been determined in four crystal forms with and without Mg++ bound, at up to 1.9 A resolution. Structural comparisons with CheY from Escherichia coli shows substantial similarity in their folds, with some concerted changes propagating away from the active site that suggest how phosphorylated CheY, a signal transduction protein in bacterial chemotaxis, is recognized by its targets. A highly conserved segment of the protein (the "y-turn loop," residues 55-61), previously suggested to be a rigid recognition determinant, is for the first time seen in two alternative conformations in the different crystal structures. Although CheY from Thermotoga has much higher thermal stability than its mesophilic counterparts, comparison of structural features previously proposed to enhance thermostability such as hydrogen bonds, ion pairs, compactness, and hydrophobic surface burial would not suggest it to be so.
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===CHEY FROM THERMOTOGA MARITIMA (MG-IV)===
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Crystal structures of CheY from Thermotoga maritima do not support conventional explanations for the structural basis of enhanced thermostability.,Usher KC, de la Cruz AF, Dahlquist FW, Swanson RV, Simon MI, Remington SJ Protein Sci. 1998 Feb;7(2):403-12. PMID:9521117<ref>PMID:9521117</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 4tmy" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_9521117}}, adds the Publication Abstract to the page
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*[[Chemotaxis protein 3D structures|Chemotaxis protein 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9521117 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_9521117}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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4TMY is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TMY OCA].
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==Reference==
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<ref group="xtra">PMID:9521117</ref><references group="xtra"/>
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[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
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[[Category: Cruz, A De La.]]
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[[Category: Dahlquist FW]]
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[[Category: Dahlquist, F W.]]
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[[Category: De La Cruz A]]
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[[Category: Remington, S J.]]
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[[Category: Remington SJ]]
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[[Category: Usher, K C.]]
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[[Category: Usher KC]]
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[[Category: Chemotaxis]]
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[[Category: Magnesium binding]]
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[[Category: Phosphoryl transfer]]
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[[Category: Signal transduction]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:57:24 2009''
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Current revision

CHEY FROM THERMOTOGA MARITIMA (MG-IV)

PDB ID 4tmy

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