3cgi

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{{Seed}}
 
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[[Image:3cgi.png|left|200px]]
 
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<!--
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==Crystal structure of the PduU shell protein from the Pdu microcompartment==
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The line below this paragraph, containing "STRUCTURE_3cgi", creates the "Structure Box" on the page.
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<StructureSection load='3cgi' size='340' side='right'caption='[[3cgi]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3cgi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CGI FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cgi OCA], [https://pdbe.org/3cgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cgi RCSB], [https://www.ebi.ac.uk/pdbsum/3cgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cgi ProSAT]</span></td></tr>
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{{STRUCTURE_3cgi| PDB=3cgi | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PDUU_SALTY PDUU_SALTY]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cg/3cgi_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cgi ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The Pdu microcompartment is a proteinaceous, subcellular structure that serves as an organelle for the metabolism of 1,2-propanediol in Salmonella enterica. It encapsulates several related enzymes within a shell composed of a few thousand protein subunits. Recent structural studies on the carboxysome, a related microcompartment involved in CO(2) fixation, have concluded that the major shell proteins from that microcompartment form hexamers that pack into layers comprising the facets of the shell. Here we report the crystal structure of PduU, a protein from the Pdu microcompartment, representing the first structure of a shell protein from a noncarboxysome microcompartment. Though PduU is a hexamer like other characterized shell proteins, it has undergone a circular permutation leading to dramatic differences in the hexamer pore. In view of the hypothesis that microcompartment metabolites diffuse across the outer shell through these pores, the unique structure of PduU suggests the possibility of a special functional role.
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===Crystal structure of the PduU shell protein from the Pdu microcompartment===
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Structure of the PduU shell protein from the Pdu microcompartment of Salmonella.,Crowley CS, Sawaya MR, Bobik TA, Yeates TO Structure. 2008 Sep 10;16(9):1324-32. PMID:18786396<ref>PMID:18786396</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<!--
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_18786396}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 3cgi" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 18786396 is the PubMed ID number.
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== References ==
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-->
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<references/>
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{{ABSTRACT_PUBMED_18786396}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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3CGI is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CGI OCA].
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Crowley CS]]
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==Reference==
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[[Category: Sawaya MR]]
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<ref group="xtra">PMID:18786396</ref><references group="xtra"/>
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[[Category: Yeates TO]]
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[[Category: Salmonella typhimurium]]
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[[Category: Crowley, C S.]]
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[[Category: Sawaya, M R.]]
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[[Category: Yeates, T O.]]
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[[Category: Bacterial microcompartment]]
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[[Category: Beta barrel]]
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[[Category: Circular permutation]]
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[[Category: Propanediol]]
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[[Category: Signaling protein]]
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[[Category: Unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 21:59:07 2009''
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Current revision

Crystal structure of the PduU shell protein from the Pdu microcompartment

PDB ID 3cgi

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