2r5k
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2r5k.png|left|200px]] | ||
| - | < | + | ==Pentamer Structure of Major Capsid protein L1 of Human Papilloma Virus type 11== |
| - | + | <StructureSection load='2r5k' size='340' side='right'caption='[[2r5k]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2r5k]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_papillomavirus_11 Human papillomavirus 11]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R5K FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r5k OCA], [https://pdbe.org/2r5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r5k RCSB], [https://www.ebi.ac.uk/pdbsum/2r5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r5k ProSAT]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VL1_HPV11 VL1_HPV11] Forms an icosahedral capsid with a T=7 symmetry and about 55 nm diameter. The capsid is composed of 72 pentamers linked to each other by disulfide bonds and associated with L2 proteins. The capsid encapsulates the genomic DNA, but does not bind DNA. Essential for the initial attachment to the host cell (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r5/2r5k_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r5k ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]] | |
| - | + | __TOC__ | |
| - | < | + | </StructureSection> |
| - | + | [[Category: Human papillomavirus 11]] | |
| - | + | [[Category: Large Structures]] | |
| - | + | [[Category: Bishop B]] | |
| - | + | [[Category: Chen XS]] | |
| - | + | [[Category: Dasgupta J]] | |
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Current revision
Pentamer Structure of Major Capsid protein L1 of Human Papilloma Virus type 11
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