1nkn
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1nkn.png|left|200px]] | ||
- | + | ==VISUALIZING AN UNSTABLE COILED COIL: THE CRYSTAL STRUCTURE OF AN N-TERMINAL SEGMENT OF THE SCALLOP MYOSIN ROD== | |
- | + | <StructureSection load='1nkn' size='340' side='right'caption='[[1nkn]], [[Resolution|resolution]] 2.50Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1nkn]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Argopecten_irradians Argopecten irradians] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NKN FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nkn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nkn OCA], [https://pdbe.org/1nkn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nkn RCSB], [https://www.ebi.ac.uk/pdbsum/1nkn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nkn ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/Q17042_ARGIR Q17042_ARGIR] [https://www.uniprot.org/uniprot/GCN4_YEAST GCN4_YEAST] Is a transcription factor that is responsible for the activation of more than 30 genes required for amino acid or for purine biosynthesis in response to amino acid or purine starvation. Binds and recognize the DNA sequence: 5'-TGA[CG]TCA-3'. | |
- | + | == Evolutionary Conservation == | |
- | + | [[Image:Consurf_key_small.gif|200px|right]] | |
- | < | + | Check<jmol> |
- | + | <jmolCheckbox> | |
- | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nk/1nkn_consurf.spt"</scriptWhenChecked> | |
- | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
- | + | <text>to colour the structure by Evolutionary Conservation</text> | |
- | + | </jmolCheckbox> | |
- | == | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nkn ConSurf]. |
- | + | <div style="clear:both"></div> | |
- | + | __TOC__ | |
- | == | + | </StructureSection> |
- | < | + | [[Category: Argopecten irradians]] |
- | [[ | + | [[Category: Large Structures]] |
- | [[ | + | [[Category: Saccharomyces cerevisiae]] |
- | [[Category: | + | [[Category: Blazsek A]] |
- | [[Category: | + | [[Category: Brown JH]] |
- | [[Category: | + | [[Category: Cohen C]] |
- | [[Category: | + | [[Category: Farkas L]] |
- | [[Category: | + | [[Category: Li Y]] |
- | [[Category: | + | [[Category: Nyitray L]] |
- | [[Category: | + | [[Category: Reshetnikova L]] |
- | [[Category: | + | |
- | + | ||
- | + |
Current revision
VISUALIZING AN UNSTABLE COILED COIL: THE CRYSTAL STRUCTURE OF AN N-TERMINAL SEGMENT OF THE SCALLOP MYOSIN ROD
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