1f97

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{{Seed}}
 
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[[Image:1f97.png|left|200px]]
 
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==SOLUBLE PART OF THE JUNCTION ADHESION MOLECULE FROM MOUSE==
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The line below this paragraph, containing "STRUCTURE_1f97", creates the "Structure Box" on the page.
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<StructureSection load='1f97' size='340' side='right'caption='[[1f97]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1f97]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F97 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1f97| PDB=1f97 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f97 OCA], [https://pdbe.org/1f97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f97 RCSB], [https://www.ebi.ac.uk/pdbsum/1f97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f97 ProSAT]</span></td></tr>
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</table>
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===SOLUBLE PART OF THE JUNCTION ADHESION MOLECULE FROM MOUSE===
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== Function ==
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[https://www.uniprot.org/uniprot/JAM1_MOUSE JAM1_MOUSE] Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_11500366}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 11500366 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f9/1f97_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_11500366}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1F97 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F97 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f97 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:11500366</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Arcy, A D.]]
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[[Category: Bazzoni G]]
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[[Category: Bazzoni, G.]]
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[[Category: Brockhaus M]]
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[[Category: Brockhaus, M.]]
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[[Category: D'Arcy A]]
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[[Category: Dale, G.]]
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[[Category: Dale G]]
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[[Category: Dejana, E.]]
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[[Category: Dejana E]]
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[[Category: Hennig, M.]]
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[[Category: Hennig M]]
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[[Category: Kostrewa, D.]]
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[[Category: Kostrewa D]]
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[[Category: Winkler, F.]]
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[[Category: Winkler F]]
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[[Category: Beta-sandwich fold]]
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[[Category: Immunoglobulin superfamily]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 23:49:10 2009''
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Current revision

SOLUBLE PART OF THE JUNCTION ADHESION MOLECULE FROM MOUSE

PDB ID 1f97

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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