This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1k6i

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:44, 7 February 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1k6i.png|left|200px]]
 
-
<!--
+
==Crystal structure of Nmra, a negative transcriptional regulator (Trigonal form)==
-
The line below this paragraph, containing "STRUCTURE_1k6i", creates the "Structure Box" on the page.
+
<StructureSection load='1k6i' size='340' side='right'caption='[[1k6i]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1k6i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_nidulans Aspergillus nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K6I FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-
{{STRUCTURE_1k6i| PDB=1k6i | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6i OCA], [https://pdbe.org/1k6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k6i RCSB], [https://www.ebi.ac.uk/pdbsum/1k6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k6i ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of Nmra, a negative transcriptional regulator (Trigonal form)===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/NMRA_EMENI NMRA_EMENI] May be a redox sensor protein. Has much higher affinity for NAD(P) than for NAD(P)H. Has similar affinity for NAD and NADP. Negative transcriptional regulator involved in the post-transcriptional modulation of the GATA-type transcription factor areA, forming part of a system controlling nitrogen metabolite repression (By similarity). Interferes with the interaction between areA and target DNA. Overexpression leads to areA inhibition.<ref>PMID:17854403</ref> <ref>PMID:12764138</ref> <ref>PMID:15537757</ref> <ref>PMID:18602114</ref>
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_11726498}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 11726498 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k6/1k6i_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_11726498}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1K6I is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Emericella_nidulans Emericella nidulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6I OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1k6i ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
== References ==
-
<ref group="xtra">PMID:11726498</ref><references group="xtra"/>
+
<references/>
-
[[Category: Emericella nidulans]]
+
__TOC__
-
[[Category: Cocklin, S.]]
+
</StructureSection>
-
[[Category: Dodds, A.]]
+
[[Category: Aspergillus nidulans]]
-
[[Category: Hawkins, A R.]]
+
[[Category: Large Structures]]
-
[[Category: Lamb, H K.]]
+
[[Category: Cocklin S]]
-
[[Category: Leslie, K.]]
+
[[Category: Dodds A]]
-
[[Category: Nichols, C E.]]
+
[[Category: Hawkins AR]]
-
[[Category: Ren, J.]]
+
[[Category: Lamb HK]]
-
[[Category: Stammers, D K.]]
+
[[Category: Leslie K]]
-
[[Category: Rossmann fold transcriptional regulation short chain dehydrogenase reductase]]
+
[[Category: Nichols CE]]
-
 
+
[[Category: Ren J]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 23:58:56 2009''
+
[[Category: Stammers DK]]

Current revision

Crystal structure of Nmra, a negative transcriptional regulator (Trigonal form)

PDB ID 1k6i

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1k6i"
Personal tools