This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2gdf

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2gdf" size="450" color="white" frame="true" align="right" spinBox="true" caption="2gdf, resolution 2.40&Aring;" /> '''Crystal structure of...)
Current revision (13:51, 13 March 2024) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2gdf.gif|left|200px]]<br /><applet load="2gdf" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2gdf, resolution 2.40&Aring;" />
 
-
'''Crystal structure of Dioclea violacea seed lectin'''<br />
 
-
==About this Structure==
+
==Crystal structure of Dioclea violacea seed lectin==
-
2GDF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Dioclea_violacea Dioclea violacea] with MN and CA as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2GDF OCA].
+
<StructureSection load='2gdf' size='340' side='right'caption='[[2gdf]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
[[Category: Dioclea violacea]]
+
== Structural highlights ==
-
[[Category: Single protein]]
+
<table><tr><td colspan='2'>[[2gdf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Macropsychanthus_violaceus Macropsychanthus violaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GDF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GDF FirstGlance]. <br>
-
[[Category: Cavada, B.S.]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
[[Category: Chornet, J.J.C.]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-
[[Category: Sol, F.Gallego.del.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gdf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gdf OCA], [https://pdbe.org/2gdf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gdf RCSB], [https://www.ebi.ac.uk/pdbsum/2gdf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gdf ProSAT]</span></td></tr>
-
[[Category: CA]]
+
</table>
-
[[Category: MN]]
+
== Function ==
-
[[Category: plant lectin]]
+
[https://www.uniprot.org/uniprot/LECA_DIOGR LECA_DIOGR] D-mannose/D-glucose-binding lectin. Has anti-inflammatory activity in rats. Induces histamine release in mast cells from rat. Induces lymphocyte proliferation and IFNG production. Shows toxicity against the aquatic snail B.glabrata at concentrations higher than 50 ug/ml.<ref>PMID:1398779</ref> <ref>PMID:7524287</ref> <ref>PMID:18472821</ref> <ref>PMID:9575151</ref> <ref>PMID:10747944</ref> <ref>PMID:19765980</ref>
-
 
+
== Evolutionary Conservation ==
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 11:08:21 2007''
+
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gd/2gdf_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gdf ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Macropsychanthus violaceus]]
 +
[[Category: Cavada BS]]
 +
[[Category: Chornet JJC]]
 +
[[Category: Gallego del Sol F]]

Current revision

Crystal structure of Dioclea violacea seed lectin

PDB ID 2gdf

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2gdf"
Personal tools