1s08

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{{Seed}}
 
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[[Image:1s08.png|left|200px]]
 
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==Crystal Structure of the D147N Mutant of 7,8-Diaminopelargonic Acid Synthase==
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The line below this paragraph, containing "STRUCTURE_1s08", creates the "Structure Box" on the page.
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<StructureSection load='1s08' size='340' side='right'caption='[[1s08]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1s08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S08 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_1s08| PDB=1s08 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s08 OCA], [https://pdbe.org/1s08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s08 RCSB], [https://www.ebi.ac.uk/pdbsum/1s08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s08 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BIOA_ECOLI BIOA_ECOLI] Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor.<ref>PMID:1092681</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s0/1s08_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s08 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of the D147N Mutant of 7,8-Diaminopelargonic Acid Synthase===
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==See Also==
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*[[7%2C8-diaminopelargonic acid synthase 3D structures|7%2C8-diaminopelargonic acid synthase 3D structures]]
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== References ==
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<references/>
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 14756557 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_14756557}}
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==About this Structure==
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1S08 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S08 OCA].
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==Reference==
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<ref group="xtra">PMID:14756557</ref><references group="xtra"/>
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[[Category: Adenosylmethionine--8-amino-7-oxononanoate transaminase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Eliot, A C.]]
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[[Category: Large Structures]]
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[[Category: Famm, K.]]
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[[Category: Eliot AC]]
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[[Category: Kirsch, J F.]]
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[[Category: Famm K]]
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[[Category: Sandmark, J.]]
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[[Category: Kirsch JF]]
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[[Category: Schneider, G.]]
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[[Category: Sandmark J]]
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[[Category: Aminotransferase]]
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[[Category: Schneider G]]
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[[Category: Fold type i]]
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[[Category: Homodimer]]
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[[Category: Subclass ii]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 01:25:25 2009''
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Current revision

Crystal Structure of the D147N Mutant of 7,8-Diaminopelargonic Acid Synthase

PDB ID 1s08

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