This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2fn4

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:29, 30 August 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2fn4.png|left|200px]]
 
-
<!--
+
==The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state==
-
The line below this paragraph, containing "STRUCTURE_2fn4", creates the "Structure Box" on the page.
+
<StructureSection load='2fn4' size='340' side='right'caption='[[2fn4]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2fn4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FN4 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
{{STRUCTURE_2fn4| PDB=2fn4 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2fn4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fn4 OCA], [https://pdbe.org/2fn4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2fn4 RCSB], [https://www.ebi.ac.uk/pdbsum/2fn4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2fn4 ProSAT]</span></td></tr>
-
 
+
</table>
-
===The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/RRAS_HUMAN RRAS_HUMAN] Regulates the organization of the actin cytoskeleton.
-
 
+
== Evolutionary Conservation ==
-
==About this Structure==
+
[[Image:Consurf_key_small.gif|200px|right]]
-
2FN4 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FN4 OCA].
+
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fn/2fn4_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2fn4 ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Large Structures]]
-
[[Category: Burgess, N.]]
+
[[Category: Arrowsmith C]]
-
[[Category: Debreczeni, J.]]
+
[[Category: Burgess N]]
-
[[Category: Delft, F von.]]
+
[[Category: Debreczeni J]]
-
[[Category: Doyle, D.]]
+
[[Category: Doyle D]]
-
[[Category: Edwards, A.]]
+
[[Category: Edwards A]]
-
[[Category: Elkins, J M.]]
+
[[Category: Elkins JM]]
-
[[Category: Gileadi, C.]]
+
[[Category: Gileadi C]]
-
[[Category: Papagrigoriou, E.]]
+
[[Category: Papagrigoriou E]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Salah E]]
-
[[Category: Salah, E.]]
+
[[Category: Sundstrom M]]
-
[[Category: Sundstrom, M.]]
+
[[Category: Turnbull AP]]
-
[[Category: Turnbull, A P.]]
+
[[Category: Weigelt J]]
-
[[Category: Weigel, J.]]
+
[[Category: Von Delft F]]
-
[[Category: Gdp/gtp binding]]
+
-
[[Category: Gtp hydrolysis]]
+
-
[[Category: Rra]]
+
-
[[Category: Sgc]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Structural genomics consortium]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 01:54:11 2009''
+

Current revision

The crystal structure of human Ras-related protein, RRAS, in the GDP-bound state

PDB ID 2fn4

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools