This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1ljr
From Proteopedia
(Difference between revisions)
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
| - | [[Image:1ljr.png|left|200px]] | ||
| - | + | ==GLUTATHIONE TRANSFERASE (HGST T2-2) FROM HUMAN== | |
| - | + | <StructureSection load='1ljr' size='340' side='right'caption='[[1ljr]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1ljr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LJR FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | --> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ljr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ljr OCA], [https://pdbe.org/1ljr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ljr RCSB], [https://www.ebi.ac.uk/pdbsum/1ljr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ljr ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GSTT2_HUMAN GSTT2_HUMAN] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lj/1ljr_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ljr ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Board | + | [[Category: Large Structures]] |
| - | [[Category: Chelvanayagam | + | [[Category: Board PG]] |
| - | [[Category: Flanagan | + | [[Category: Chelvanayagam G]] |
| - | [[Category: Mckinstry | + | [[Category: Flanagan J]] |
| - | [[Category: Oakley | + | [[Category: Mckinstry WJ]] |
| - | [[Category: Parker | + | [[Category: Oakley AJ]] |
| - | [[Category: Rossjohn | + | [[Category: Parker MW]] |
| - | [[Category: Tan | + | [[Category: Rossjohn J]] |
| - | [[Category: Verger | + | [[Category: Tan KL]] |
| - | + | [[Category: Verger D]] | |
| - | + | ||
| - | + | ||
Current revision
GLUTATHIONE TRANSFERASE (HGST T2-2) FROM HUMAN
| |||||||||||
Categories: Homo sapiens | Large Structures | Board PG | Chelvanayagam G | Flanagan J | Mckinstry WJ | Oakley AJ | Parker MW | Rossjohn J | Tan KL | Verger D

