2p0k
From Proteopedia
(Difference between revisions)
(7 intermediate revisions not shown.) | |||
Line 1: | Line 1: | ||
- | {{Seed}} | ||
- | [[Image:2p0k.png|left|200px]] | ||
- | < | + | ==Crystal structure of SCMH1== |
- | + | <StructureSection load='2p0k' size='340' side='right'caption='[[2p0k]], [[Resolution|resolution]] 1.75Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2p0k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P0K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P0K FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p0k OCA], [https://pdbe.org/2p0k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p0k RCSB], [https://www.ebi.ac.uk/pdbsum/2p0k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p0k ProSAT]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/SCMH1_HUMAN SCMH1_HUMAN] Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes (By similarity). | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p0/2p0k_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p0k ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | == | + | ==See Also== |
- | + | *[[Polycomb complex proteins 3D structures|Polycomb complex proteins 3D structures]] | |
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
- | [[Category: Bochkarev | + | [[Category: Arrowsmith CH]] |
- | [[Category: Crombet | + | [[Category: Bochkarev A]] |
- | [[Category: Edwards | + | [[Category: Crombet L]] |
- | [[Category: Herzanych | + | [[Category: Edwards AM]] |
- | [[Category: Kozieradzki | + | [[Category: Herzanych N]] |
- | [[Category: Liu | + | [[Category: Kozieradzki I]] |
- | [[Category: Loppnau | + | [[Category: Liu Y]] |
- | [[Category: Min | + | [[Category: Loppnau P]] |
- | + | [[Category: Min J]] | |
- | [[Category: Senisterra | + | [[Category: Senisterra G]] |
- | [[Category: Sundstrom | + | [[Category: Sundstrom M]] |
- | [[Category: Vedadi | + | [[Category: Vedadi M]] |
- | [[Category: Weigelt | + | [[Category: Weigelt J]] |
- | + | ||
- | + | ||
- | + | ||
- | + | ||
- | + | ||
- | + |
Current revision
Crystal structure of SCMH1
|
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bochkarev A | Crombet L | Edwards AM | Herzanych N | Kozieradzki I | Liu Y | Loppnau P | Min J | Senisterra G | Sundstrom M | Vedadi M | Weigelt J