2b6h
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:2b6h.png|left|200px]] | ||
- | + | ==Structure of human ADP-ribosylation factor 5== | |
- | + | <StructureSection load='2b6h' size='340' side='right'caption='[[2b6h]], [[Resolution|resolution]] 1.76Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2b6h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B6H FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.764Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b6h OCA], [https://pdbe.org/2b6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b6h RCSB], [https://www.ebi.ac.uk/pdbsum/2b6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b6h ProSAT]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/ARF5_HUMAN ARF5_HUMAN] GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. | |
- | + | == Evolutionary Conservation == | |
- | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | + | Check<jmol> | |
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/2b6h_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b6h ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
- | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
- | [[Category: Atanassova | + | [[Category: Arrowsmith C]] |
- | [[Category: Bochkarev | + | [[Category: Atanassova A]] |
- | [[Category: Dimov | + | [[Category: Bochkarev A]] |
- | [[Category: Edwards | + | [[Category: Dimov S]] |
- | [[Category: Lew | + | [[Category: Edwards A]] |
- | [[Category: Park | + | [[Category: Lew J]] |
- | + | [[Category: Park H]] | |
- | [[Category: Shehab | + | [[Category: Shehab I]] |
- | [[Category: Sundarajan | + | [[Category: Sundarajan E]] |
- | [[Category: Sundstrom | + | [[Category: Sundstrom M]] |
- | [[Category: Tempel | + | [[Category: Tempel W]] |
- | [[Category: Weigelt | + | [[Category: Weigelt J]] |
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Current revision
Structure of human ADP-ribosylation factor 5
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Atanassova A | Bochkarev A | Dimov S | Edwards A | Lew J | Park H | Shehab I | Sundarajan E | Sundstrom M | Tempel W | Weigelt J