1elr

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{{Seed}}
 
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[[Image:1elr.png|left|200px]]
 
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==Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD==
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The line below this paragraph, containing "STRUCTURE_1elr", creates the "Structure Box" on the page.
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<StructureSection load='1elr' size='340' side='right'caption='[[1elr]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1elr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ELR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ELR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
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{{STRUCTURE_1elr| PDB=1elr | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1elr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1elr OCA], [https://pdbe.org/1elr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1elr RCSB], [https://www.ebi.ac.uk/pdbsum/1elr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1elr ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/STIP1_HUMAN STIP1_HUMAN] Mediates the association of the molecular chaperones HSC70 and HSP90 (HSPCA and HSPCB).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/el/1elr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1elr ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD===
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==See Also==
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*[[HOP protein|HOP protein]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_10786835}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 10786835 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10786835}}
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==About this Structure==
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1ELR is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ELR OCA].
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==Reference==
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<ref group="xtra">PMID:10786835</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Brinker, A.]]
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[[Category: Large Structures]]
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[[Category: Hartl, F U.]]
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[[Category: Brinker A]]
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[[Category: Moarefi, I.]]
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[[Category: Hartl FU]]
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[[Category: Scheufler, C.]]
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[[Category: Moarefi I]]
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[[Category: Helical repeat]]
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[[Category: Scheufler C]]
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[[Category: Hop]]
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[[Category: Hsp90]]
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[[Category: Peptide-complex]]
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[[Category: Protein binding]]
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[[Category: Tpr-domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:16:39 2009''
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Current revision

Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD

PDB ID 1elr

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