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3bji

From Proteopedia

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{{Seed}}
 
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[[Image:3bji.png|left|200px]]
 
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<!--
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==Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1==
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The line below this paragraph, containing "STRUCTURE_3bji", creates the "Structure Box" on the page.
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<StructureSection load='3bji' size='340' side='right'caption='[[3bji]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3bji]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BJI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BJI FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_3bji| PDB=3bji | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3bji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3bji OCA], [https://pdbe.org/3bji PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3bji RCSB], [https://www.ebi.ac.uk/pdbsum/3bji PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3bji ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VAV_HUMAN VAV_HUMAN] Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bj/3bji_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3bji ConSurf].
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<div style="clear:both"></div>
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===Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1===
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==See Also==
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*[[Rac 3D structures|Rac 3D structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_18589439}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 18589439 is the PubMed ID number.
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{{ABSTRACT_PUBMED_18589439}}
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==About this Structure==
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3BJI is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BJI OCA].
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==Reference==
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<ref group="xtra">PMID:18589439</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Brooun, A.]]
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[[Category: Large Structures]]
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[[Category: Chrencik, J E.]]
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[[Category: Brooun A]]
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[[Category: Kuhn, P.]]
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[[Category: Chrencik JE]]
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[[Category: Adp-ribosylation]]
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[[Category: Kuhn P]]
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[[Category: Alternative splicing]]
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[[Category: Atypical cysteine rich domain]]
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[[Category: Gef/gtpase]]
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[[Category: Gtp-binding]]
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[[Category: Guanine-nucleotide releasing factor]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Metal-binding]]
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[[Category: Methylation]]
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[[Category: Nucleotide-binding]]
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[[Category: Phorbol-ester binding]]
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[[Category: Phosphoprotein]]
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[[Category: Polymorphism]]
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[[Category: Prenylation]]
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[[Category: Protein-protein interaction]]
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[[Category: Proto-oncogene]]
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[[Category: Sh2 domain]]
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[[Category: Sh3 domain]]
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[[Category: Signaling protein]]
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[[Category: Zinc]]
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[[Category: Zinc-finger]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:06:24 2009''
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Current revision

Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1

PDB ID 3bji

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