3ba1
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:3ba1.png|left|200px]] | ||
| - | + | ==Structure of hydroxyphenylpyruvate reductase from coleus blumei== | |
| - | + | <StructureSection load='3ba1' size='340' side='right'caption='[[3ba1]], [[Resolution|resolution]] 1.47Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3ba1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plectranthus_scutellarioides Plectranthus scutellarioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BA1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BA1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.47Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ba1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ba1 OCA], [https://pdbe.org/3ba1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ba1 RCSB], [https://www.ebi.ac.uk/pdbsum/3ba1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ba1 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/HPPR_PLESU HPPR_PLESU] Catalyzes the NAD(P)H-dependent reduction of 4-hydroxyphenylpyruvate to 4-hydroxyphenyllactate and 3,4-dihydroxyphenylpyruvate to 3,4-dihydroxyphenyllactate in the biosynthesis of rosmarinic acid. Rosmarinic acid is an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid. NADP is the preferred substrate.<ref>PMID:15284489</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | == | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | [[ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/3ba1_consurf.spt"</scriptWhenChecked> |
| - | [[ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [ | + | </jmolCheckbox> |
| - | [[ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ba1 ConSurf]. |
| - | [ | + | <div style="clear:both"></div> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | + | [[Category: Plectranthus scutellarioides]] | |
| - | + | [[Category: Heine A]] | |
| + | [[Category: Janiak V]] | ||
| + | [[Category: Klebe G]] | ||
| + | [[Category: Petersen M]] | ||
Current revision
Structure of hydroxyphenylpyruvate reductase from coleus blumei
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