2p4v

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{{Seed}}
 
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[[Image:2p4v.png|left|200px]]
 
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==Crystal structure of the transcript cleavage factor, GreB at 2.6A resolution==
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The line below this paragraph, containing "STRUCTURE_2p4v", creates the "Structure Box" on the page.
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<StructureSection load='2p4v' size='340' side='right'caption='[[2p4v]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2p4v]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2P4V FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2p4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2p4v OCA], [https://pdbe.org/2p4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2p4v RCSB], [https://www.ebi.ac.uk/pdbsum/2p4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2p4v ProSAT]</span></td></tr>
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{{STRUCTURE_2p4v| PDB=2p4v | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GREB_ECOLI GREB_ECOLI] Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.[HAMAP-Rule:MF_00930]<ref>PMID:8431948</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/p4/2p4v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2p4v ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the transcript cleavage factor, GreB at 2.6A resolution===
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==See Also==
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_17917675}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 17917675 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_17917675}}
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==About this Structure==
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2P4V is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2P4V OCA].
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==Reference==
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<ref group="xtra">PMID:17917675</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Artsimovitch, I.]]
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[[Category: Large Structures]]
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[[Category: Dearborn, A D.]]
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[[Category: Artsimovitch I]]
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[[Category: Klyuyev, S.]]
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[[Category: Dearborn AD]]
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[[Category: Svetlov, V.]]
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[[Category: Klyuyev S]]
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[[Category: Vassylyev, D G.]]
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[[Category: Svetlov V]]
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[[Category: Vassylyeva, M N.]]
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[[Category: Vassylyev DG]]
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[[Category: Crystal structure]]
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[[Category: Vassylyeva MN]]
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[[Category: Gre-factor]]
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[[Category: Rna polymerase]]
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[[Category: Transcript cleavage]]
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[[Category: Transcription]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:18:53 2009''
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Current revision

Crystal structure of the transcript cleavage factor, GreB at 2.6A resolution

PDB ID 2p4v

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