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1ls2

From Proteopedia

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{{Seed}}
 
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[[Image:1ls2.png|left|200px]]
 
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==Fitting of EF-Tu and tRNA in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome==
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The line below this paragraph, containing "STRUCTURE_1ls2", creates the "Structure Box" on the page.
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<SX load='1ls2' size='340' side='right' viewer='molstar' caption='[[1ls2]], [[Resolution|resolution]] 16.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ls2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LS2 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 16.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ls2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ls2 OCA], [https://pdbe.org/1ls2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ls2 RCSB], [https://www.ebi.ac.uk/pdbsum/1ls2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ls2 ProSAT]</span></td></tr>
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{{STRUCTURE_1ls2| PDB=1ls2 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/EFTU2_ECOLI EFTU2_ECOLI] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.[HAMAP-Rule:MF_00118] May play an important regulatory role in cell growth and in the bacterial response to nutrient deprivation.[HAMAP-Rule:MF_00118]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ls/1ls2_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ls2 ConSurf].
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<div style="clear:both"></div>
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===Fitting of EF-Tu and tRNA in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome===
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==See Also==
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*[[Elongation factor 3D structures|Elongation factor 3D structures]]
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__TOC__
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</SX>
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The line below this paragraph, {{ABSTRACT_PUBMED_12093756}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12093756 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12093756}}
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==About this Structure==
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1LS2 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LS2 OCA].
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==Reference==
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<ref group="xtra">PMID:12093756</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Agrawal, R K.]]
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[[Category: Agrawal RK]]
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[[Category: Burkhardt, N.]]
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[[Category: Burkhardt N]]
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[[Category: Frank, J.]]
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[[Category: Frank J]]
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[[Category: Grassucci, R A.]]
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[[Category: Grassucci RA]]
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[[Category: Nierhaus, K H.]]
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[[Category: Nierhaus KH]]
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[[Category: Sengupta, J.]]
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[[Category: Sengupta J]]
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[[Category: Swami, N K.]]
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[[Category: Swami NK]]
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[[Category: Valle, M.]]
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[[Category: Valle M]]
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[[Category: 70s e coli ribosome]]
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[[Category: Cryo-em]]
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[[Category: Ef-tu]]
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[[Category: Ternary complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:36:32 2009''
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Current revision

Fitting of EF-Tu and tRNA in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome

1ls2, resolution 16.80Å

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