1n1c

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{{Seed}}
 
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[[Image:1n1c.png|left|200px]]
 
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==Crystal Structure Of The Dimeric TorD Chaperone From Shewanella Massilia==
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The line below this paragraph, containing "STRUCTURE_1n1c", creates the "Structure Box" on the page.
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<StructureSection load='1n1c' size='340' side='right'caption='[[1n1c]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1n1c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shewanella_massilia Shewanella massilia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N1C FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTT:2,3-DIHYDROXY-1,4-DITHIOBUTANE'>DTT</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1n1c| PDB=1n1c | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n1c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n1c OCA], [https://pdbe.org/1n1c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n1c RCSB], [https://www.ebi.ac.uk/pdbsum/1n1c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n1c ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TORD_SHEMA TORD_SHEMA] Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n1/1n1c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n1c ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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TorD is the cytoplasmic chaperone involved in the maturation of the molybdoenzyme TorA prior to the translocation of the folded protein into the periplasm. The X-ray structure at 2.4 A resolution of the TorD dimer reveals extreme domain swapping between the two subunits. The all-helical architecture of the globular domains within the intertwined molecular dimer shows no similarity with known protein structures. According to sequence similarities, this new fold probably represents the architecture of the chaperones associated with the bacterial DMSO/TMAO reductases and also that of proteins of yet unknown functions. The occurrence of multiple oligomeric forms and the chaperone activity of both monomeric and dimeric TorD raise questions about the possible biological role of domain swapping in this protein.
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===Crystal Structure Of The Dimeric TorD Chaperone From Shewanella Massilia===
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A novel protein fold and extreme domain swapping in the dimeric TorD chaperone from Shewanella massilia.,Tranier S, Iobbi-Nivol C, Birck C, Ilbert M, Mortier-Barriere I, Mejean V, Samama JP Structure. 2003 Feb;11(2):165-74. PMID:12575936<ref>PMID:12575936</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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The line below this paragraph, {{ABSTRACT_PUBMED_12575936}}, adds the Publication Abstract to the page
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<div class="pdbe-citations 1n1c" style="background-color:#fffaf0;"></div>
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(as it appears on PubMed at http://www.pubmed.gov), where 12575936 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_12575936}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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1N1C is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Shewanella_massilia Shewanella massilia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1C OCA].
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==Reference==
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<ref group="xtra">PMID:12575936</ref><references group="xtra"/>
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[[Category: Shewanella massilia]]
[[Category: Shewanella massilia]]
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[[Category: Birck, C.]]
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[[Category: Birck C]]
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[[Category: Iobbi-Nivol, C.]]
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[[Category: Iobbi-Nivol C]]
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[[Category: Mejean, V.]]
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[[Category: Mejean V]]
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[[Category: Mortier-Barriere, I.]]
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[[Category: Mortier-Barriere I]]
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[[Category: Samama, J P.]]
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[[Category: Samama J-P]]
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[[Category: Tranier, S.]]
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[[Category: Tranier S]]
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[[Category: 3d-domain swapping]]
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[[Category: Chaperone]]
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[[Category: Tord]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:47:42 2009''
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Current revision

Crystal Structure Of The Dimeric TorD Chaperone From Shewanella Massilia

PDB ID 1n1c

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